PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16754782-4	2006	Dexamethasone and N-[2-(cyclohexyloxyl)-4-nitrophenyl]-methane sulfonamide (NS-398; a selective COX-2 inhibitor) attenuated TNF-alpha-induced expression of COX-2 and activated productions PGE2 and PGI2.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	76-82	tumor necrosis factor	Rattus norvegicus	124-133	
11094044-10	2000	Interestingly, the generation of TNF-alpha and the associated cardiodepression caused by LPS were reduced by indomethacin, NS-398 and the Tx-receptor antagonist daltroban.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	123-129	tumor necrosis factor	Rattus norvegicus	33-42	
15916752-5	2005	Similar results were also obtained in the rat cranial window model where treatment with the COX-2 inhibitor, NS-398 (0.1 microM), or the NF-kappaB inhibitor, PDTC (10 microM), significantly reduced the permeability increases produced by TNF.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	109-115	tumor necrosis factor	Rattus norvegicus	237-240	
11376495-15	2001	Treatment with NS-398 and Vioxx, which caused only a moderate decrease in the PGE(2) generation in the non-ulcerated gastric mucosa, delayed ulcer healing and attenuated significantly the GBF at ulcer margin and PGE(2) generation in the ulcerated tissue, while raising the plasma IL-1beta and TNFalpha similarly to those observed in indomethacin- and ASA-treated rats.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	15-21	tumor necrosis factor	Rattus norvegicus	293-301	
9875706-3	1998	The TNFalpha-induced SWS enhancement, fever and anorexia were all blocked by co-infusion of diclofenac, a non-selective cyclooxygenase (COX) inhibitor, and by pretreatment with NS-398, a COX-2-specific inhibitor.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	177-183	tumor necrosis factor	Rattus norvegicus	4-12	
28522561-4	2017	Second, the immediate phase of this potentiating effect of TNFalpha was completely abolished by a pretreatment with a selective cyclooxygenase-2 (COX-2) inhibitor, NS-398, whereas the delayed potentiation was only partially attenuated.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	164-170	tumor necrosis factor	Rattus norvegicus	59-67