PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11161582-6 2001 NS-398 (a specific inhibitor of PGHS-2) and indomethacin (an inhibitor of both PGHS-1 and PGHS-2) both inhibited prostaglandin production by homogenates of day 22 and day 29 placenta. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide 0-6 prostaglandin G/H synthase 2 Cavia porcellus 32-38 15306209-0 2004 Antitussive effect of NS-398, a selective cyclooxygenase-2 inhibitor, in guinea pigs. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide 22-28 prostaglandin G/H synthase 2 Cavia porcellus 42-58 11815376-3 2002 The present work therefore compared the actions of diclofenac, ibuprofen, indomethacin, and the cyclo-oxygenase-2 selective inhibitor, NS-398, on a primary culture of guinea-pig gastric mucous epithelial cells. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide 135-141 prostaglandin G/H synthase 2 Cavia porcellus 96-113 11161582-8 2001 Indomethacin and NS-398 were both very effective at inhibiting the outputs of PGF(2 alpha), PGE2 and 6-keto-PGF(1 alpha)from the day 22 and day 29 placenta and sub-placenta in culture, indicating that prostaglandin production by the guinea-pig placenta and sub-placenta in culture is largely dependent upon the activity of PGHS-2. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide 17-23 prostaglandin G/H synthase 2 Cavia porcellus 323-329 10718109-6 1999 NS-398, a relatively specific inhibitor of PGHS-2, also prevented the inhibitory action of exogenous arachidonic acid. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide 0-6 prostaglandin G/H synthase 2 Cavia porcellus 43-49 8958831-0 1996 Effect of a selective prostaglandin H synthase-2 inhibitor (NS-398) on prostaglandin production by the guinea-pig uterus. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide 60-66 prostaglandin G/H synthase 2 Cavia porcellus 22-48 8958831-2 1996 NS-398, a selective inhibitor of prostaglandin H synthase-2 (PGHS-2), also inhibited PG synthesis by endometrial homogenates, by cultured endometrium and myometrium, and by cultured epithelial glandular cells and stromal cells. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide 0-6 prostaglandin G/H synthase 2 Cavia porcellus 33-59 8958831-2 1996 NS-398, a selective inhibitor of prostaglandin H synthase-2 (PGHS-2), also inhibited PG synthesis by endometrial homogenates, by cultured endometrium and myometrium, and by cultured epithelial glandular cells and stromal cells. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide 0-6 prostaglandin G/H synthase 2 Cavia porcellus 61-67 8789408-3 1995 It is now known that indomethacin nonselectively inhibits COX-1 and COX-2, whereas NS-398 is a selective inhibitor of COX-2. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide 83-89 prostaglandin G/H synthase 2 Cavia porcellus 118-123