PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18951856-5	2008	The method was successfully applied to determine the IC(50) value of the known mPGES-1 inhibitor NS-398.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	97-103	prostaglandin E synthase	Mus musculus	79-86	
20128796-6	2010	The protective effect of NS-398 on the excitotoxicity observed in WT slices was completely abolished in mPGES-1 KO slices, which showed less excitotoxicity than WT slices.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	25-31	prostaglandin E synthase	Mus musculus	104-111	
17258197-8	2007	In contrast, COX-2 inhibitors, nimesulide and NS-398, had no effect on the exudate volume, but they increased the number of COX-2- and mPGES-1-expressing cells and extension of their dendritic processes with significant increase in the COX-2 level, which were antagonised by ketorolac.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	46-52	prostaglandin E synthase	Mus musculus	135-142	
15590979-5	2004	However, pretreatment of the luteal cells with a selective COX-II inhibitor, NS-398, abolished the VEGF-enhanced mPGES mRNA expression.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	77-83	prostaglandin E synthase	Mus musculus	113-118	
15458923-8	2005	N-(2-cyclohexyloxy-4-nitrophenyl)-methanesulfonamide (NS-398), a selective COX-2 inhibitor, totally inhibited PGE2 production at both the 8-h and 24-h time points, suggesting that COX-2-dependent PGE2 generation does not depend on mPGES-1 activity at the early stage.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	54-60	prostaglandin E synthase	Mus musculus	231-238	
14558087-8	2003	RESULTS: The enhanced expression of mPGES mRNA and protein in IL-1beta-stimulated RASFs was attenuated by the addition of indomethacin, NS-398, rofecoxib, or meloxicam.	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	136-142	prostaglandin E synthase	Mus musculus	36-41