PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19704105-10	2009	A subdepressor dose of candesartan abolished the SAD-induced left ventricular/myocyte hypertrophy, myocardial fibrosis, macrophage infiltration, and inductions of monocyte chemoattractant protein-1, transforming growth factor-beta, and angiotensinogen and subsequently prevented systolic dysfunction in SHRs with SAD.	candesartan	23-34	C-C motif chemokine ligand 2	Rattus norvegicus	163-197	
26499133-11	2015	Candesartan significantly reduced the protein expression and activity of iNOS, the activity of NF-kappaB p65, and the gene expression levels of MCP-1 and AP-1 in the rat model of acute myocardial infarction.	candesartan	0-11	C-C motif chemokine ligand 2	Rattus norvegicus	144-149	
26499133-14	2015	These results suggested that candesartan ameliorates acute myocardial infarction in rats through iNOS, NF-kappaB, MCP-1 and AP-1, and the restoration of HSP72.	candesartan	29-40	C-C motif chemokine ligand 2	Rattus norvegicus	114-119	
10469372-5	1999	RESULTS: Time-dependent elevation of MCP-1 expression was dramatically suppressed by treatment with the angiotensin-converting enzyme inhibitor enalapril or the AT1 receptor antagonist candesartan, and was closely associated with effects on proteinuria and glomerular macrophage number.	candesartan	185-196	C-C motif chemokine ligand 2	Rattus norvegicus	37-42	
25825359-7	2015	Both candesartan and BM-MSCs ameliorated renal function and reduced significantly the inflammatory markers (TNF-alpha , NF-kappaB, p38-MAPK and MCP-1) and apoptotic markers (caspase-3 and Bax) in renal tissue after CDDP injection.	candesartan	5-16	C-C motif chemokine ligand 2	Rattus norvegicus	144-149	
20490358-5	2010	An ELISA-based cytokine array revealed that candesartan normalized elevated renal interleukin (IL) 1-beta and monocyte chemoattractant protein-1 (MCP-1) levels in OZ.	candesartan	44-55	C-C motif chemokine ligand 2	Rattus norvegicus	110-144	
20490358-5	2010	An ELISA-based cytokine array revealed that candesartan normalized elevated renal interleukin (IL) 1-beta and monocyte chemoattractant protein-1 (MCP-1) levels in OZ.	candesartan	44-55	C-C motif chemokine ligand 2	Rattus norvegicus	146-151	
17249527-9	2006	Moreover, candesartan decreased MCP-1 induction and macrophage infiltration at day 3 and prevented myocardial fibrosis at day 14, without affecting left ventricle and myocyte hypertrophy.	candesartan	10-21	C-C motif chemokine ligand 2	Rattus norvegicus	32-37	
16079469-7	2005	The improvement of DHF by candesartan was accompanied by the decrease in cardiac hypertrophy, fibrosis, and apoptosis, and the reduction of gene expression of brain natriuretic peptide, collagen I, and monocyte chemoattractant protein-1.	candesartan	26-37	C-C motif chemokine ligand 2	Rattus norvegicus	202-236