PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24168234-1 2015 OBJECTIVE: The aim of the study is to explore the pharmacokinetic behavior of candesartan solid dispersions prepared by different pharmaceutical interventions using P-gp inhibitor in rabbits to validate the effectiveness of naringin as a pharmaceutical excipient in enhancing the oral delivery of lipophilic candesartan cilexetil. candesartan 78-89 ATP-dependent translocase ABCB1 Oryctolagus cuniculus 165-169 24168234-7 2015 CONCLUSION: These results are quite stimulating for further development of a clinically useful oral formulation of candesartan cilexetil based on P-gp inhibition using naringin, a natural flavonoid as a pharmaceutical excipient. candesartan 115-126 ATP-dependent translocase ABCB1 Oryctolagus cuniculus 146-150