PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27216792-6	2016	RESULTS: Based on the literatures published, it has been demonstrated that pharmacokinetic interactions of losartan with other agents are mainly via CYP2C9- and CYP3A4-mediated, the role played by CYP enzyme system in the metabolism of valsartan, candesartan, irbesartan, and azilsartan appears modest, and cytochrome P450 system has no influence on the metabolism of telmisartan, eprosartan, olmesartan.	candesartan	247-258	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	161-167	
33446524-11	2021	Significance Statement This study demonstrates that the acyl glucuronidation of candesartan to form candesartan acyl-beta-D-glucuronide enhances CYP2C8 inhibition while exerting minimal effects on CYP3A4, OATP1B1, and OATP1B3.	candesartan	80-91	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	197-203