PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17903697-9	2007	Candesartan increased ACE2 mRNA levels in the heart.	candesartan	0-11	angiotensin I converting enzyme 2	Rattus norvegicus	22-26	
33479758-3	2021	In the lung of healthy rats, we observed that candesartan (an angiotensin type-1, AT1, receptor blocker; ARB) and captopril (an ACE inhibitor; ACEI) up-regulated expression of tissue ACE2 and RAS anti-inflammatory axis receptors (AT2 and Mas receptors).	candesartan	46-57	angiotensin I converting enzyme 2	Rattus norvegicus	183-187	
33881142-7	2021	(2021), 135, 465-481) showed in rats that captopril and candesartan up-regulated ACE2 expression and the protective RAS pathway in lung tissue.	candesartan	56-67	angiotensin I converting enzyme 2	Rattus norvegicus	81-85	
34400868-5	2021	Candesartan and CoQ10 as well as their combination suppressed gastrocnemius content of angiotensin II while they raised angiotensin-converting enzyme 2 (ACE2) activity, angiotensin (1-7) expression, and Mas receptor mRNA level.	candesartan	0-11	angiotensin I converting enzyme 2	Rattus norvegicus	120-151	
34400868-5	2021	Candesartan and CoQ10 as well as their combination suppressed gastrocnemius content of angiotensin II while they raised angiotensin-converting enzyme 2 (ACE2) activity, angiotensin (1-7) expression, and Mas receptor mRNA level.	candesartan	0-11	angiotensin I converting enzyme 2	Rattus norvegicus	153-157	
22120037-7	2012	Candesartan improved the functional markers in a dose-dependent manner and also upregulated Ang (1-7), ACE2 and mas1 in the myocardium of DCM rats.	candesartan	0-11	angiotensin I converting enzyme 2	Rattus norvegicus	103-107