PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22543084-7	2012	When administered interperitoneally in the OIR model, candesartan reduced the upregulation of VEGF receptor-2 in the retina, but had no effects in the other angiogenesis-related genes, such as HIF-1alpha, VEGF-A, and VEGF receptor-1.	candesartan	54-65	hypoxia inducible factor 1 subunit alpha	Homo sapiens	193-203	
34032365-4	2021	In the present study, an integrated amphiphilic system (RSCD) is designed based on Angiotensin II receptor blocker candesartan for siRNA delivery against the hypoxia-inducible factor-1 alpha (HIF-1alpha), aiming at both vascular and cellular "relaxation" to reconstruct a tumor normoxic microenvironment.	candesartan	115-126	hypoxia inducible factor 1 subunit alpha	Homo sapiens	158-190