PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18594792-12 2008 The combined effect of candesartan and rosuvastatin was superior in reducing macrophage infiltration, monocyte chemoattractant protein-1 level, vascular AGE accumulation and RAGE abundance in the vascular wall. candesartan 23-34 advanced glycosylation end product-specific receptor Mus musculus 174-178 15574998-7 2004 RESULTS: Kidneys from KK/Ta mice showed increased formation of AGEs, nitro-oxidative stress and RAGE expression and these were attenuated by candesartan treatment. candesartan 141-152 advanced glycosylation end product-specific receptor Mus musculus 96-100 15574998-11 2004 CONCLUSIONS: These findings suggest that candesartan, an ARB, reduces AGE accumulation and subsequent albuminuria by down-regulating the NADPH oxidase p47phox component and iNOS expression and by attenuating RAGE expression in type 2 diabetic KK/Ta mouse kidneys. candesartan 41-52 advanced glycosylation end product-specific receptor Mus musculus 208-212