PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19427347-2 2009 The IL-6 release was significantly suppressed by Y-27632 and fasudil, Rho-kinase inhibitors. fasudil 61-68 interleukin 6 Rattus norvegicus 4-8 32308124-9 2020 Administration of the selective inhibitor of ROCK, fasudil, significantly reduced myocardial infarct size, myocyte apoptosis, and inflammatory cytokine, including interleukin 6 and tumor necrosis factor alpha. fasudil 51-58 interleukin 6 Rattus norvegicus 163-176 35428330-10 2022 RESULTS: Fasudil effectively prevented inflammatory injury induced by LPS, which is manifested by the decrease of pro-inflammatory cytokines interleukin-6 (IL-6) and monocyte chenotactic protein-1 (MCP-1). fasudil 9-16 interleukin 6 Rattus norvegicus 141-154 35428330-10 2022 RESULTS: Fasudil effectively prevented inflammatory injury induced by LPS, which is manifested by the decrease of pro-inflammatory cytokines interleukin-6 (IL-6) and monocyte chenotactic protein-1 (MCP-1). fasudil 9-16 interleukin 6 Rattus norvegicus 156-160 30462329-9 2019 Treatment with Fasudil decreased the expression of proinflammatory factors, including tumor necrosis factor-alpha, inducible nitric oxide synthase, interleukin-1beta, and interleukin-6; furthermore, it inactivated the nuclear factor kappa-light-chain-enhancer of activated B cells pathway. fasudil 15-22 interleukin 6 Rattus norvegicus 171-184 30221694-4 2018 Administration of fasudil led to reductions in polymorphonuclear neutrophil counts, and the protein concentrations of tumor necrosis factor-alpha, interleukin (IL)-1beta and IL-6 in the bronchoalveolar lavage fluid of rats with sepsis-induced ALI. fasudil 18-25 interleukin 6 Rattus norvegicus 174-178 30088170-5 2018 When compared to rats with PQ-induced lung injuries, rats pretreated with fasudil had significantly fewer polymorphonuclear neutrophils and lower concentrations of protein, TNF-alpha, IL-1beta, and IL-6 in their bronchoalveolar lavage fluid. fasudil 74-81 interleukin 6 Rattus norvegicus 198-202