PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24276076-1 2014 As the first in class steroid 17alpha-hydroxylase/C17,20-lyase (CYP17) inhibitor, abiraterone acetate (of which the active metabolite is abiraterone) has been shown to improve overall survival in patients with castration-resistant prostate cancer (CRPC)--in those who are chemotherapy-naive and those previously treated with docetaxel. Abiraterone Acetate 82-101 cytokine like 1 Homo sapiens 50-53 23023354-3 2012 Abiraterone acetate is an orally active, potent and selective inhibitor of 17 a hydroxylase and c 17, 20 lyase, which acts by decreasing the de novo production of androgens with no rise in steroids downstream. Abiraterone Acetate 0-19 cytokine like 1 Homo sapiens 96-110