PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17666045-4 2007 Here we demonstrate that in mouse cortical neurons, inhibition of the Ca(2+)-dependent protein phosphatase calcineurin by FK506 or cyclosporine A blocks CREB-dependent gene expression induced by depolarization without inhibiting depolarization-induced Ca(2+) influx or CREB Ser-133 phosphorylation. Cyclosporine 131-145 cAMP responsive element binding protein 1 Mus musculus 153-157