PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15567778-0	2004	[Effects of cyclosporine A on NIT-1 beta cell proliferation and pol alpha1 gene expression in vitro].	Cyclosporine	12-26	nitrilase 1	Mus musculus	30-35	
15567778-1	2004	OBJECTIVE: To investigate the effects of cyclosporine A on the proliferation and pol alpha1 mRNA expression of cultured NIT-1 beta cells.	Cyclosporine	41-55	nitrilase 1	Mus musculus	120-125	
15567778-2	2004	METHODS: After exposure to cyclosporine A at various concentrations (0.05 to 10 micromol/L) for 48 h and 72 h, NIT-1 cell proliferation was analyzed by MTT assay and the gene expression determined by reverse transcriptional PCR (RT-PCR).	Cyclosporine	27-41	nitrilase 1	Mus musculus	111-116	
15567778-4	2004	CONCLUSION: Cyclosporine A can effectively inhibit the proliferation of NIT-1 cells possibly through down-regulating the expression of pol alpha1 mRNA.	Cyclosporine	12-26	nitrilase 1	Mus musculus	72-77	
16027085-1	2005	OBJECTIVE: To observe the effects of cyclosporin A (CsA) on gene expression profiles of NIT-1 pancreatic beta cells cell line using microarray technique.	Cyclosporine	52-55	nitrilase 1	Mus musculus	88-93	
16027085-6	2005	CONCLUSIONS: CsA treatment for 24 h induces changes in the gene expression profiles of NIT-1 pancreatic beta cells.	Cyclosporine	13-16	nitrilase 1	Mus musculus	87-92