PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30587068-9	2019	MDR1 overexpression increased the resistance of LLC-PK1 cells to tacrolimus, cyclosporine A, sirolimus and everolimus.	Cyclosporine	77-91	ATP-binding cassette, sub-family B (MDR/TAP), member 1	Sus scrofa	0-4	
21918035-7	2011	However, vectorial transport across LLC-OCT1/MDR1 cells was identified, which was inhibited by the MDR1 inhibitor cyclosporine A, clearly indicating that YM155 is in fact a substrate of MDR1.	Cyclosporine	114-128	ATP-binding cassette, sub-family B (MDR/TAP), member 1	Sus scrofa	99-103	
21918035-7	2011	However, vectorial transport across LLC-OCT1/MDR1 cells was identified, which was inhibited by the MDR1 inhibitor cyclosporine A, clearly indicating that YM155 is in fact a substrate of MDR1.	Cyclosporine	114-128	ATP-binding cassette, sub-family B (MDR/TAP), member 1	Sus scrofa	45-49	
21918035-7	2011	However, vectorial transport across LLC-OCT1/MDR1 cells was identified, which was inhibited by the MDR1 inhibitor cyclosporine A, clearly indicating that YM155 is in fact a substrate of MDR1.	Cyclosporine	114-128	ATP-binding cassette, sub-family B (MDR/TAP), member 1	Sus scrofa	99-103	
11856485-4	2002	The K(i) values for P-gp of cyclosporine and verapamil were 1.09 and 540 microM, respectively, and that of bromocriptine was 6.52 microM in a calcein-AM efflux assay using porcine kidney epithelial LLC-PK1 and L-MDR1 cells, overexpressing human P-gp.	Cyclosporine	28-40	ATP-binding cassette, sub-family B (MDR/TAP), member 1	Sus scrofa	212-216	
18054347-9	2008	Cyclosporin A (CyA) restored the sensitivity, intracellular accumulation and transport activity for both drugs in L-MDR1 cells.	Cyclosporine	0-13	ATP-binding cassette, sub-family B (MDR/TAP), member 1	Sus scrofa	116-120	
11463358-7	2001	Its translocation across the apical membrane was greatly stimulated by the expression of MDR1 Pgp, and inhibited by the MDR1 inhibitors PSC833 and cyclosporin A.	Cyclosporine	147-160	ATP-binding cassette, sub-family B (MDR/TAP), member 1	Sus scrofa	89-93	
11463358-7	2001	Its translocation across the apical membrane was greatly stimulated by the expression of MDR1 Pgp, and inhibited by the MDR1 inhibitors PSC833 and cyclosporin A.	Cyclosporine	147-160	ATP-binding cassette, sub-family B (MDR/TAP), member 1	Sus scrofa	120-124	
11042226-4	2000	Polarised transport of doxorubicin in the Caco-2 and the LLC-PK1:MDR1 cell lines could be inhibited by the P-gp inhibitors SDZ-PSC 833 (PSC 833), cyclosporin A (CsA), verapamil and quinine, but not by the inhibitors for the organic cation carrier systems cimetidine and tetraethylammonium (TEA).	Cyclosporine	146-159	ATP-binding cassette, sub-family B (MDR/TAP), member 1	Sus scrofa	65-69