PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23153588-0	2013	Cyclosporine A and PSC833 inhibit ABCA1 function via direct binding.	Cyclosporine	0-14	phospholipid-transporting ATPase ABCA1	Mesocricetus auratus	34-39	
23153588-3	2013	Cyclosporine A inhibits ABCA1-mediated cholesterol efflux, but it is not clear whether this is mediated via inhibition of calcineurin.	Cyclosporine	0-14	phospholipid-transporting ATPase ABCA1	Mesocricetus auratus	24-29	
23153588-4	2013	We analyzed the effects of cyclosporine A and related compounds on ABCA1 function in BHK/ABCA1 cells.	Cyclosporine	27-41	phospholipid-transporting ATPase ABCA1	Mesocricetus auratus	67-72	
23153588-5	2013	Cyclosporine A, FK506, and pimecrolimus inhibited ABCA1-mediated cholesterol efflux in a concentration-dependent manner, with IC(50) of 7.6, 13.6, and 7.0muM, respectively.	Cyclosporine	0-14	phospholipid-transporting ATPase ABCA1	Mesocricetus auratus	50-55	
23153588-9	2013	Furthermore, a non-immunosuppressive cyclosporine, PSC833, inhibited ABCA1-mediated cholesterol efflux with IC(50) of 1.9muM, and efficiently competed with [(3)H] cyclosporine A binding to ABCA1.	Cyclosporine	37-49	phospholipid-transporting ATPase ABCA1	Mesocricetus auratus	69-74	
23153588-9	2013	Furthermore, a non-immunosuppressive cyclosporine, PSC833, inhibited ABCA1-mediated cholesterol efflux with IC(50) of 1.9muM, and efficiently competed with [(3)H] cyclosporine A binding to ABCA1.	Cyclosporine	37-49	phospholipid-transporting ATPase ABCA1	Mesocricetus auratus	189-194	
23153588-9	2013	Furthermore, a non-immunosuppressive cyclosporine, PSC833, inhibited ABCA1-mediated cholesterol efflux with IC(50) of 1.9muM, and efficiently competed with [(3)H] cyclosporine A binding to ABCA1.	Cyclosporine	163-177	phospholipid-transporting ATPase ABCA1	Mesocricetus auratus	69-74	
23153588-10	2013	These results indicate that cyclosporine A and PSC833 inhibit ABCA1 via direct binding, and that the ABCA1 inhibitor PSC833 is an excellent candidate for further investigations of the detailed mechanisms underlying formation of HDL.	Cyclosporine	28-42	phospholipid-transporting ATPase ABCA1	Mesocricetus auratus	62-67