PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10573060-8 1999 Nuclear extracts from the CsA-treated DC revealed a decrease in nuclear translocation of NF-kappaB (p50). Cyclosporine 26-29 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 89-98 10573060-10 1999 Addition of IL-4 from the start of DC cultures conferred resistance to CsA-induced inhibition of NF-kappaB nuclear translocation and DC maturation. Cyclosporine 71-74 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 97-106 2595372-2 1989 Cyclosporin A was found to specifically inhibit the appearance of DNA binding activity of NF-AT, AP-3, and to a lesser extent NF-kappa B, nuclear proteins that appear to be important in the transcriptional activation of the genes for interleukin-2 and its receptor, as well as several other lymphokines. Cyclosporine 0-13 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 126-136 32529968-6 2020 The molecular mechanisms underlying the effects of CsA were explored, and it was found that CsA could inhibit the increase in CypA, p-Akt, NF-kappaB, and MMP-9 protein expression after middle cerebral artery occlusion, while Claudin-5 expression was decreased. Cyclosporine 92-95 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 139-148 26324318-6 2015 These cytokines and LPS can induce P-gp expression through the STAT3/Nf-kappab pathway, contributing to a decrease of cyclosporine A retention, which can be reversed by the application of a P-gp inhibitor. Cyclosporine 118-132 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 69-78 19454717-0 2009 Suppression of NF-kappaB by cyclosporin a and tacrolimus (FK506) via induction of the C/EBP family: implication for unfolded protein response. Cyclosporine 28-41 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 15-24 19454717-7 2009 In TNF-alpha-treated cells, suppression of MCP-1 by CsA or FK506 was associated with blunted responses of NF-kappaB, the crucial regulator of MCP-1. Cyclosporine 52-55 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 106-115 19454717-9 2009 CsA and FK506, as well as other UPR inducers, caused up-regulation of C/EBP family members, especially C/EBPbeta and CHOP (C/EBP homologous protein), and overexpression of either C/EBPbeta or CHOP significantly attenuated TNF-alpha-triggered NF-kappaB activation. Cyclosporine 0-3 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 242-251 8029023-0 1994 Cyclosporin A sensitivity of the NF-kappa B site of the IL2R alpha promoter in untransformed murine T cells. Cyclosporine 0-13 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 33-43 8029023-9 1994 Based on these results, we propose that the NF-kappa B site of the IL2R alpha promoter mediates at least part of the CsA sensitivity of IL2R alpha gene induction in untransformed T cells, possibly because de novo synthesis of p105 NF-kappa B is required for sustained IL2R alpha expression. Cyclosporine 117-120 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 44-54 8029023-9 1994 Based on these results, we propose that the NF-kappa B site of the IL2R alpha promoter mediates at least part of the CsA sensitivity of IL2R alpha gene induction in untransformed T cells, possibly because de novo synthesis of p105 NF-kappa B is required for sustained IL2R alpha expression. Cyclosporine 117-120 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 226-230 8029023-9 1994 Based on these results, we propose that the NF-kappa B site of the IL2R alpha promoter mediates at least part of the CsA sensitivity of IL2R alpha gene induction in untransformed T cells, possibly because de novo synthesis of p105 NF-kappa B is required for sustained IL2R alpha expression. Cyclosporine 117-120 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 231-241 29309904-9 2018 This increased response were diminished by etoricoxib, furegrelate, SQ 29548, cyclosporine A and parthenolide, inhibitors of COX-2, TXA2 synthase, TP receptors, calcineurin and NF-kappaB, respectively. Cyclosporine 78-92 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 177-186 19399405-0 2009 The effects of PDTC plus leflunomide and cyclosporine on the NF-kappaB signaling pathway in mouse-to-rat cardiac xenografts. Cyclosporine 41-53 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 61-70 19399405-1 2009 In this study, the effects of pirrolidine dithiocarbamate (PDTC) plus leflunomide (Lef) and cyclosporine (CsA) on the NF-kappaB signaling pathway in mouse-to-rat cardiac xeno-transplantation models were investigated. Cyclosporine 92-104 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 118-127