PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21912224-4	2011	The translocation activity of NFAT5 was assessed by confocal microscopy and Western immunoblotting after CsA treatment.	Cyclosporine	105-108	nuclear factor of activated T cells 5	Homo sapiens	30-35	
21912224-8	2011	Transcriptional activities of NF-kappaB, AP-1, and NFAT1 were not stimulated by CsA; however, nuclear translocation of NFAT5 was markedly upregulated by CsA.	Cyclosporine	153-156	nuclear factor of activated T cells 5	Homo sapiens	119-124	
21912224-9	2011	CsA-induced NGF production was markedly decreased on inhibition of NFAT5 or SB20429.	Cyclosporine	0-3	nuclear factor of activated T cells 5	Homo sapiens	67-72	
21912224-11	2011	These results suggest that CsA mediates NGF expression through activation of p38 and NFAT5.	Cyclosporine	27-30	nuclear factor of activated T cells 5	Homo sapiens	85-90	
17202415-5	2007	This study tested the hypothesis that long-term CsA treatment reduces the salinity/tonicity of the renal medullary interstitium as a result of inhibition of active sodium transporters, leading to downregulation of TonEBP.	Cyclosporine	48-51	nuclear factor of activated T cells 5	Homo sapiens	214-220	
17202415-8	2007	Conversely, 28 d of CsA treatment led to downregulation of TonEBP and overt nephrotoxicity.	Cyclosporine	20-23	nuclear factor of activated T cells 5	Homo sapiens	59-65	
17202415-12	2007	It is concluded that the downregulation of TonEBP in the setting of long-term CsA administration is secondary to the reduced tonicity of the renal medullary interstitium.	Cyclosporine	78-81	nuclear factor of activated T cells 5	Homo sapiens	43-49	
27486749-0	2016	In Vitro Inhibition of NFAT5-Mediated Induction of CCL2 in Hyperosmotic Conditions by Cyclosporine and Dexamethasone on Human HeLa-Modified Conjunctiva-Derived Cells.	Cyclosporine	86-98	nuclear factor of activated T cells 5	Homo sapiens	23-28	
27486749-3	2016	This work was completed by an analysis of the effects of cyclosporine A (CsA), dexamethasone (Dex) and doxycycline (Dox) on HO-induced CCL2 and NFAT5 induction.	Cyclosporine	73-76	nuclear factor of activated T cells 5	Homo sapiens	144-149	
19956430-11	2009	Cyclosporin A induces nuclear membrane translocation of NFAT-5 in cultured keratinocytes and raffinose (a hypertonicity inducing agent) induces more nuclear localization of NFAT-5 compared to untreated cells.	Cyclosporine	0-13	nuclear factor of activated T cells 5	Homo sapiens	56-62	
19956430-14	2009	CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses.	Cyclosporine	0-3	nuclear factor of activated T cells 5	Homo sapiens	29-35	
19956430-14	2009	CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses.	Cyclosporine	0-3	nuclear factor of activated T cells 5	Homo sapiens	36-42	
19956430-14	2009	CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses.	Cyclosporine	0-3	nuclear factor of activated T cells 5	Homo sapiens	122-128	
19956430-14	2009	CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses.	Cyclosporine	0-3	nuclear factor of activated T cells 5	Homo sapiens	129-135	
19956430-14	2009	CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses.	Cyclosporine	0-3	nuclear factor of activated T cells 5	Homo sapiens	122-128	
19956430-14	2009	CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses.	Cyclosporine	0-3	nuclear factor of activated T cells 5	Homo sapiens	129-135	
17202415-4	2007	It was reported recently that long-term CsA treatment was associated with decreased renal expression of TonEBP target genes, including aquaporin-2, urea transporter, and aldose reductase.	Cyclosporine	40-43	nuclear factor of activated T cells 5	Homo sapiens	104-110	
11046013-6	2000	The induction of NFATL1 protein, as well as NFATL1-dependent transcription, is inhibited by cyclosporin A and FK506, and expression of constitutively active calcineurin induces NFATL1-dependent transcription.	Cyclosporine	92-105	nuclear factor of activated T cells 5	Homo sapiens	17-23	
11046013-6	2000	The induction of NFATL1 protein, as well as NFATL1-dependent transcription, is inhibited by cyclosporin A and FK506, and expression of constitutively active calcineurin induces NFATL1-dependent transcription.	Cyclosporine	92-105	nuclear factor of activated T cells 5	Homo sapiens	44-50	
11046013-6	2000	The induction of NFATL1 protein, as well as NFATL1-dependent transcription, is inhibited by cyclosporin A and FK506, and expression of constitutively active calcineurin induces NFATL1-dependent transcription.	Cyclosporine	92-105	nuclear factor of activated T cells 5	Homo sapiens	44-50