PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21912224-4 2011 The translocation activity of NFAT5 was assessed by confocal microscopy and Western immunoblotting after CsA treatment. Cyclosporine 105-108 nuclear factor of activated T cells 5 Homo sapiens 30-35 11046013-6 2000 The induction of NFATL1 protein, as well as NFATL1-dependent transcription, is inhibited by cyclosporin A and FK506, and expression of constitutively active calcineurin induces NFATL1-dependent transcription. Cyclosporine 92-105 nuclear factor of activated T cells 5 Homo sapiens 17-23 11046013-6 2000 The induction of NFATL1 protein, as well as NFATL1-dependent transcription, is inhibited by cyclosporin A and FK506, and expression of constitutively active calcineurin induces NFATL1-dependent transcription. Cyclosporine 92-105 nuclear factor of activated T cells 5 Homo sapiens 44-50 11046013-6 2000 The induction of NFATL1 protein, as well as NFATL1-dependent transcription, is inhibited by cyclosporin A and FK506, and expression of constitutively active calcineurin induces NFATL1-dependent transcription. Cyclosporine 92-105 nuclear factor of activated T cells 5 Homo sapiens 44-50 27486749-0 2016 In Vitro Inhibition of NFAT5-Mediated Induction of CCL2 in Hyperosmotic Conditions by Cyclosporine and Dexamethasone on Human HeLa-Modified Conjunctiva-Derived Cells. Cyclosporine 86-98 nuclear factor of activated T cells 5 Homo sapiens 23-28 27486749-3 2016 This work was completed by an analysis of the effects of cyclosporine A (CsA), dexamethasone (Dex) and doxycycline (Dox) on HO-induced CCL2 and NFAT5 induction. Cyclosporine 73-76 nuclear factor of activated T cells 5 Homo sapiens 144-149 21912224-8 2011 Transcriptional activities of NF-kappaB, AP-1, and NFAT1 were not stimulated by CsA; however, nuclear translocation of NFAT5 was markedly upregulated by CsA. Cyclosporine 153-156 nuclear factor of activated T cells 5 Homo sapiens 119-124 21912224-9 2011 CsA-induced NGF production was markedly decreased on inhibition of NFAT5 or SB20429. Cyclosporine 0-3 nuclear factor of activated T cells 5 Homo sapiens 67-72 21912224-11 2011 These results suggest that CsA mediates NGF expression through activation of p38 and NFAT5. Cyclosporine 27-30 nuclear factor of activated T cells 5 Homo sapiens 85-90 19956430-11 2009 Cyclosporin A induces nuclear membrane translocation of NFAT-5 in cultured keratinocytes and raffinose (a hypertonicity inducing agent) induces more nuclear localization of NFAT-5 compared to untreated cells. Cyclosporine 0-13 nuclear factor of activated T cells 5 Homo sapiens 56-62 19956430-14 2009 CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses. Cyclosporine 0-3 nuclear factor of activated T cells 5 Homo sapiens 29-35 19956430-14 2009 CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses. Cyclosporine 0-3 nuclear factor of activated T cells 5 Homo sapiens 36-42 19956430-14 2009 CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses. Cyclosporine 0-3 nuclear factor of activated T cells 5 Homo sapiens 122-128 19956430-14 2009 CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses. Cyclosporine 0-3 nuclear factor of activated T cells 5 Homo sapiens 129-135 19956430-14 2009 CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses. Cyclosporine 0-3 nuclear factor of activated T cells 5 Homo sapiens 122-128 19956430-14 2009 CsA and raffinose effects on NFAT-5/TonEBP in cultured keratinocytes suggest diverse intracellular signaling pathways for NFAT-5/TonEBP in these cells, and that NFAT-5/TonEBP might function to translate different extracellular stimuli into appropriate functional responses. Cyclosporine 0-3 nuclear factor of activated T cells 5 Homo sapiens 129-135 17202415-4 2007 It was reported recently that long-term CsA treatment was associated with decreased renal expression of TonEBP target genes, including aquaporin-2, urea transporter, and aldose reductase. Cyclosporine 40-43 nuclear factor of activated T cells 5 Homo sapiens 104-110 17202415-5 2007 This study tested the hypothesis that long-term CsA treatment reduces the salinity/tonicity of the renal medullary interstitium as a result of inhibition of active sodium transporters, leading to downregulation of TonEBP. Cyclosporine 48-51 nuclear factor of activated T cells 5 Homo sapiens 214-220 17202415-8 2007 Conversely, 28 d of CsA treatment led to downregulation of TonEBP and overt nephrotoxicity. Cyclosporine 20-23 nuclear factor of activated T cells 5 Homo sapiens 59-65 17202415-12 2007 It is concluded that the downregulation of TonEBP in the setting of long-term CsA administration is secondary to the reduced tonicity of the renal medullary interstitium. Cyclosporine 78-81 nuclear factor of activated T cells 5 Homo sapiens 43-49