PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12490546-8	2003	Stimulation of transfected cells with AngII or specific AT2-receptor agonists resulted in a significant increase in eNOS promoter activity, which was blocked by CsA, MCIP1, and mutation of an upstream NF-AT site.	Cyclosporine	161-164	nitric oxide synthase 3	Rattus norvegicus	116-120	
9530528-5	1998	CsA inhibited cNOS activity of rat ventricles and failed to bring about changes in their iNOS activity.	Cyclosporine	0-3	nitric oxide synthase 3	Rattus norvegicus	14-18	
7582858-5	1995	CsA in all concentrations significantly (P < 0.001) inhibited both Ca2+ ATPase and NOS activities of rat myocardium and FDP at 1000 microM concentration completely reversed the 1000 microM CsA-inhibited Ca2+ ATPase and cNOS activities of rat myocardium.	Cyclosporine	0-3	nitric oxide synthase 3	Rattus norvegicus	222-226	
7582858-5	1995	CsA in all concentrations significantly (P < 0.001) inhibited both Ca2+ ATPase and NOS activities of rat myocardium and FDP at 1000 microM concentration completely reversed the 1000 microM CsA-inhibited Ca2+ ATPase and cNOS activities of rat myocardium.	Cyclosporine	192-195	nitric oxide synthase 3	Rattus norvegicus	222-226	
32822562-0	2021	Nicorandil prevents the nephrotoxic effect of cyclosporine-A in albino rats through modulation of HIF-1alpha/VEGF /eNOS signaling.	Cyclosporine	46-60	nitric oxide synthase 3	Rattus norvegicus	115-119	
32822562-9	2021	Cyclosporine decreased the renal expression levels (P<0.001) of HIF-1alpha, eNOS, and VEGF inducing endothelial dysfunction and the triggered inflammation, and upregulated the pro-fibrotic marker transforming growth factor (TGF-beta).	Cyclosporine	0-12	nitric oxide synthase 3	Rattus norvegicus	76-80	
32822562-13	2021	Nicorandil reversed the disturbed HIF-1alpha/VEGF/eNOS pathway created by cyclosporine.	Cyclosporine	74-86	nitric oxide synthase 3	Rattus norvegicus	50-54	
33096599-8	2020	In contrast, CsA induced arteriolopathy, hypoperfusion, a reduction in the glomerular filtration rate, and downregulation of eNOS, angiotensinogen, and AT1R mRNA levels.	Cyclosporine	13-16	nitric oxide synthase 3	Rattus norvegicus	125-129