PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29540150-0 2018 Expression of brain-derived neurotrophic factor in kidneys from normal and cyclosporine-treated rats. Cyclosporine 75-87 brain-derived neurotrophic factor Rattus norvegicus 14-47 29540150-3 2018 The present study examined the expression of BDNF and tropomyosin-related kinase (Trk) receptors in an experimental model of chronic cyclosporine A (CsA) nephropathy. Cyclosporine 133-147 brain-derived neurotrophic factor Rattus norvegicus 45-49 29540150-3 2018 The present study examined the expression of BDNF and tropomyosin-related kinase (Trk) receptors in an experimental model of chronic cyclosporine A (CsA) nephropathy. Cyclosporine 149-152 brain-derived neurotrophic factor Rattus norvegicus 45-49 29540150-10 2018 By contrast, the expression of these factors decreased in kidneys from CsA-treated rats (BDNF: 51.1 +- 19.5% vs. 102.0 +- 30.3%, p < 0.01). Cyclosporine 71-74 brain-derived neurotrophic factor Rattus norvegicus 89-93 29540150-13 2018 CONCLUSIONS: BDNF is expressed in the collecting duct of the kidney and may be associated with urine-concentrating ability in an experimental model of chronic CsA-induced nephropathy. Cyclosporine 159-162 brain-derived neurotrophic factor Rattus norvegicus 13-17 20361354-0 2010 Chronic administration of cyclosporine A changes expression of BDNF and TrkB in rat hippocampus and midbrain. Cyclosporine 26-40 brain-derived neurotrophic factor Rattus norvegicus 63-67 11516824-7 2001 Reverse transcription-polymerase chain reaction revealed prolonged maintenance of BDNF mRNA expression in the CA1 sector of cyclosporin A-treated animals. Cyclosporine 124-137 brain-derived neurotrophic factor Rattus norvegicus 82-86 11516824-8 2001 The protein expression of BDNF and TrkB appeared to be up-regulated in cyclosporin A-treated animals, whereas it was transiently up-regulated but decreased to the marginal level of expression without cyclosporin A.From these results we suggest that cyclosporin A induces pCREB by an inhibition of calcineurin, resulting in the induction of BDNF. Cyclosporine 71-84 brain-derived neurotrophic factor Rattus norvegicus 26-30 11516824-8 2001 The protein expression of BDNF and TrkB appeared to be up-regulated in cyclosporin A-treated animals, whereas it was transiently up-regulated but decreased to the marginal level of expression without cyclosporin A.From these results we suggest that cyclosporin A induces pCREB by an inhibition of calcineurin, resulting in the induction of BDNF. Cyclosporine 71-84 brain-derived neurotrophic factor Rattus norvegicus 340-344 11516824-8 2001 The protein expression of BDNF and TrkB appeared to be up-regulated in cyclosporin A-treated animals, whereas it was transiently up-regulated but decreased to the marginal level of expression without cyclosporin A.From these results we suggest that cyclosporin A induces pCREB by an inhibition of calcineurin, resulting in the induction of BDNF. Cyclosporine 200-213 brain-derived neurotrophic factor Rattus norvegicus 26-30 11516824-8 2001 The protein expression of BDNF and TrkB appeared to be up-regulated in cyclosporin A-treated animals, whereas it was transiently up-regulated but decreased to the marginal level of expression without cyclosporin A.From these results we suggest that cyclosporin A induces pCREB by an inhibition of calcineurin, resulting in the induction of BDNF. Cyclosporine 200-213 brain-derived neurotrophic factor Rattus norvegicus 26-30 11516824-9 2001 The mechanisms by which cyclosporin A protects the CA1 region from neuronal cell death in forebrain ischemia may involve the interaction of pCREB, BDNF and TrkB. Cyclosporine 24-37 brain-derived neurotrophic factor Rattus norvegicus 147-151 19393753-0 2009 Effect of FK506 and cyclosporine A on the expression of BDNF, tyrosine kinase B and p75 neurotrophin receptors in astrocytes exposed to simulated ischemia in vitro. Cyclosporine 20-34 brain-derived neurotrophic factor Rattus norvegicus 56-60 19393753-1 2009 We investigated whether the immunosuppressive drugs, FK506 and cyclosporine A, increase BDNF protein and/or mRNA expression in ischemic astrocytes and if an increase could be related to changes in the nuclear expression of p-CREB, p-Erk1/2 and p-Akt. Cyclosporine 63-77 brain-derived neurotrophic factor Rattus norvegicus 88-92 19393753-4 2009 FK506 and cyclosporine A (at 1000nM and 0.25microM, respectively) stimulated the expression and release of BDNF in cultured rat cerebral cortical astrocytes exposed to OGD. Cyclosporine 10-24 brain-derived neurotrophic factor Rattus norvegicus 107-111 11516824-0 2001 Involvement of the brain-derived neurotrophic factor/TrkB pathway in neuroprotecive effect of cyclosporin A in forebrain ischemia. Cyclosporine 94-107 brain-derived neurotrophic factor Rattus norvegicus 19-52 11516824-5 2001 Based on these observations, we attempted to investigate how cyclosporin A treatment would affect the changes of phosphorylated CREB (pCREB), BDNF and its receptor tyrosine kinase B (TrkB) after forebrain ischemia in rats. Cyclosporine 61-74 brain-derived neurotrophic factor Rattus norvegicus 142-146