PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32595898-10 2020 Furthermore, double knockdown with pluripotency-associated transcription factor Nanog showed that the down-regulation of Oct4/Nanog by lentiviral infection significantly inhibited CsA-stimulated cell growth (p < 0.05). Cyclosporine 180-183 Nanog homeobox Homo sapiens 80-85 32595898-10 2020 Furthermore, double knockdown with pluripotency-associated transcription factor Nanog showed that the down-regulation of Oct4/Nanog by lentiviral infection significantly inhibited CsA-stimulated cell growth (p < 0.05). Cyclosporine 180-183 Nanog homeobox Homo sapiens 126-131 30895027-7 2017 In addition, downregulation of Nanog by lentiviral infection significantly inhibited CsA-stimulated cell growth in HGFs (P < 0.05). Cyclosporine 85-88 Nanog homeobox Homo sapiens 31-36 30895027-8 2017 Conclusion: CsA upregulated Nanog expression and cell growth in HGFs, while silencing Nanog effectively reversed these phenomena. Cyclosporine 12-15 Nanog homeobox Homo sapiens 28-33 30895027-9 2017 Nanog may act as a major switch in the pathogenesis of CsA-induced gingival overgrowth. Cyclosporine 55-58 Nanog homeobox Homo sapiens 0-5 30895027-3 2017 Materials and methods: The effect of CsA on HGFs was used to elucidate whether Nanog expression could be induced by CsA using quantitative real-time reverse transcription-polymerase chain reaction and Western blotting. Cyclosporine 37-40 Nanog homeobox Homo sapiens 79-84 30895027-3 2017 Materials and methods: The effect of CsA on HGFs was used to elucidate whether Nanog expression could be induced by CsA using quantitative real-time reverse transcription-polymerase chain reaction and Western blotting. Cyclosporine 116-119 Nanog homeobox Homo sapiens 79-84 30895027-4 2017 Cell growth in CsA-treated HGFs with Nanog lentivirus-mediated short hairpin RNA interference knockdown was evaluated by tetrazolium bromide reduction assay. Cyclosporine 15-18 Nanog homeobox Homo sapiens 37-42 30895027-5 2017 Results: CsA upregulated Nanog transcript in HGFs in a dose-dependent manner (P < 0.05). Cyclosporine 9-12 Nanog homeobox Homo sapiens 25-30 30895027-6 2017 CsA was also shown to increase Nanog protein expression in HGFs in a dose-dependent manner (P < 0.05). Cyclosporine 0-3 Nanog homeobox Homo sapiens 31-36