PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10075015-7 1999 These results indicate that CsA suppresses NO synthesis in L929 cells independent of calcineurin inhibition, and interfering with intracellular pathways involved in the iNOS induction, rather than inhibiting its enzymatic activity. Cyclosporine 28-31 nitric oxide synthase 2, inducible Mus musculus 169-173 27147271-12 2016 However, GM-CSF + CsA-induced MDSCs express higher iNOS than control MDSCs. Cyclosporine 18-21 nitric oxide synthase 2, inducible Mus musculus 51-55 27147271-13 2016 Blocking iNOS activity by inhibitor or gene deletion significantly reversed the inhibitory effects of GM-CSF + CsA-induced MDSCs on T cell proliferation. Cyclosporine 111-114 nitric oxide synthase 2, inducible Mus musculus 9-13 24970700-3 2014 Selective inhibition of NFAT by cyclosporine A and a competitive peptide inhibitor 11R-VIVIT inhibited endotoxin-induced expression of iNOS and nitric oxide (NO) release. Cyclosporine 32-46 nitric oxide synthase 2, inducible Mus musculus 135-139 14741691-3 2004 iNOS expression and NO secretion in response to LPS were suppressed by Ca(2+) antagonists (TMB-8, BAPTA/AM, and nifedipine) and CN inhibitor (cyclosporin A). Cyclosporine 142-155 nitric oxide synthase 2, inducible Mus musculus 0-4 10510443-8 1999 Cyclosporin A, but not FK506, suppressed expression of mRNA for NOS2 in a concentration-dependent manner when co-incubated with LPS. Cyclosporine 0-13 nitric oxide synthase 2, inducible Mus musculus 64-68 10510443-10 1999 Cyclosporin A suppresses NOS2 gene transcription, but FK506 acts post-transcriptionally to suppress NO generation in VSMC. Cyclosporine 0-13 nitric oxide synthase 2, inducible Mus musculus 25-29 32302594-10 2020 This effect was iNOS-dependent because pretreatment of a low dose of aminoguanidine (20 mg/kg) 15 min before the administration of a low dose of cyclosporine (1 mg/kg) reversed the proconvulsant action of sildenafil (40 mg/kg). Cyclosporine 145-157 nitric oxide synthase 2, inducible Mus musculus 16-20 12538738-12 2003 eNOS was significantly reduced in the endothelium of arterioles in the kidneys of mice treated with CsA, whereas iNOS was induced in the cortical tubules. Cyclosporine 100-103 nitric oxide synthase 2, inducible Mus musculus 113-117 10778917-8 2000 RESULTS: Cyclosporin (1-5 microg/ml) and rapamycin (1.0-10 nM) but not FK-506 (5-10 nM) inhibited both iNOS and COX-2 expression at mRNA level which led to significant inhibition of NO and PGE2 production. Cyclosporine 9-20 nitric oxide synthase 2, inducible Mus musculus 103-107 10778917-10 2000 Inhibition of iNOS and COX-2 mRNA accumulation by cyclosporin and rapamycin seem to be distinct. Cyclosporine 50-61 nitric oxide synthase 2, inducible Mus musculus 14-18