PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10075015-7	1999	These results indicate that CsA suppresses NO synthesis in L929 cells independent of calcineurin inhibition, and interfering with intracellular pathways involved in the iNOS induction, rather than inhibiting its enzymatic activity.	Cyclosporine	28-31	nitric oxide synthase 2, inducible	Mus musculus	169-173	
27147271-12	2016	However, GM-CSF + CsA-induced MDSCs express higher iNOS than control MDSCs.	Cyclosporine	18-21	nitric oxide synthase 2, inducible	Mus musculus	51-55	
27147271-13	2016	Blocking iNOS activity by inhibitor or gene deletion significantly reversed the inhibitory effects of GM-CSF + CsA-induced MDSCs on T cell proliferation.	Cyclosporine	111-114	nitric oxide synthase 2, inducible	Mus musculus	9-13	
24970700-3	2014	Selective inhibition of NFAT by cyclosporine A and a competitive peptide inhibitor 11R-VIVIT inhibited endotoxin-induced expression of iNOS and nitric oxide (NO) release.	Cyclosporine	32-46	nitric oxide synthase 2, inducible	Mus musculus	135-139	
14741691-3	2004	iNOS expression and NO secretion in response to LPS were suppressed by Ca(2+) antagonists (TMB-8, BAPTA/AM, and nifedipine) and CN inhibitor (cyclosporin A).	Cyclosporine	142-155	nitric oxide synthase 2, inducible	Mus musculus	0-4	
10510443-8	1999	Cyclosporin A, but not FK506, suppressed expression of mRNA for NOS2 in a concentration-dependent manner when co-incubated with LPS.	Cyclosporine	0-13	nitric oxide synthase 2, inducible	Mus musculus	64-68	
10510443-10	1999	Cyclosporin A suppresses NOS2 gene transcription, but FK506 acts post-transcriptionally to suppress NO generation in VSMC.	Cyclosporine	0-13	nitric oxide synthase 2, inducible	Mus musculus	25-29	
32302594-10	2020	This effect was iNOS-dependent because pretreatment of a low dose of aminoguanidine (20 mg/kg) 15 min before the administration of a low dose of cyclosporine (1 mg/kg) reversed the proconvulsant action of sildenafil (40 mg/kg).	Cyclosporine	145-157	nitric oxide synthase 2, inducible	Mus musculus	16-20	
12538738-12	2003	eNOS was significantly reduced in the endothelium of arterioles in the kidneys of mice treated with CsA, whereas iNOS was induced in the cortical tubules.	Cyclosporine	100-103	nitric oxide synthase 2, inducible	Mus musculus	113-117	
10778917-8	2000	RESULTS: Cyclosporin (1-5 microg/ml) and rapamycin (1.0-10 nM) but not FK-506 (5-10 nM) inhibited both iNOS and COX-2 expression at mRNA level which led to significant inhibition of NO and PGE2 production.	Cyclosporine	9-20	nitric oxide synthase 2, inducible	Mus musculus	103-107	
10778917-10	2000	Inhibition of iNOS and COX-2 mRNA accumulation by cyclosporin and rapamycin seem to be distinct.	Cyclosporine	50-61	nitric oxide synthase 2, inducible	Mus musculus	14-18