PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35092471-8	2022	Moreover, we found that ferulic acid remarkably prevented cyclosporine-mediated nephrotoxicity by restoring the anti-oxidant system through activating the Nrf2/HO-1 axis.	Cyclosporine	58-70	NFE2 like bZIP transcription factor 2	Rattus norvegicus	155-159	
32040235-0	2020	Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway.	Cyclosporine	31-45	NFE2 like bZIP transcription factor 2	Rattus norvegicus	83-87	
16612258-10	2006	The detrimental effects of CsA were associated with upregulation of myocardial atrial natriuretic peptide (ANP) mRNA expression, paradoxical activation of the renin-angiotensin system (RAS), induction of renal reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase, and overexpression of oxidative stress-induced transcription factor NRF2.	Cyclosporine	27-30	NFE2 like bZIP transcription factor 2	Rattus norvegicus	347-351	
16612258-13	2006	CsA-induced myocardial ANP and connective tissue growth factor (CTGF) mRNA overexpression, RAS activation, NADPH oxidase induction, and NRF2 overexpression were prevented by LA.	Cyclosporine	0-3	NFE2 like bZIP transcription factor 2	Rattus norvegicus	136-140