PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24244623-0	2013	Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells.	Cyclosporine	70-84	nerve growth factor	Homo sapiens	12-31	
34350891-11	2022	The levels of autoantibodies against NGF are decreased by the immunomodulatory activity of cyclosporin A, which mainly controls pain and improves motor function and sensitivity.	Cyclosporine	91-104	nerve growth factor	Homo sapiens	37-40	
24244623-3	2013	Considering that nerve growth factor exerts beneficial effects in the treatment of major central and peripheral neurodegenerative diseases, skin and corneal ulcers, we asked whether nerve growth factor could also exert a role in Cyclosporine A-induced graft nephrotoxicity.	Cyclosporine	229-243	nerve growth factor	Homo sapiens	182-201	
24244623-4	2013	Our hypothesis was raised from basic evidence indicating that Cyclosporine A-inhibition of calcineurin-NFAT pathway increases nerve growth factor expression levels.	Cyclosporine	62-76	nerve growth factor	Homo sapiens	126-145	
24244623-5	2013	Therefore, we investigated the involvement of nerve growth factor and its receptors in the damage exerted by Cyclosporine A in tubular renal cells, HK-2.	Cyclosporine	109-123	nerve growth factor	Homo sapiens	46-65	
24244623-6	2013	Our results showed that in HK-2 cells combined treatment with Cyclosporine A + nerve growth factor induced a significant reduction in cell vitality concomitant with a down-regulation of Cyclin D1 and up-regulation of p21 levels respect to cells treated with Cyclosporine A alone.	Cyclosporine	62-76	nerve growth factor	Homo sapiens	79-98	
24244623-6	2013	Our results showed that in HK-2 cells combined treatment with Cyclosporine A + nerve growth factor induced a significant reduction in cell vitality concomitant with a down-regulation of Cyclin D1 and up-regulation of p21 levels respect to cells treated with Cyclosporine A alone.	Cyclosporine	258-272	nerve growth factor	Homo sapiens	79-98	
24244623-10	2013	We describe two new mechanisms by which nerve growth factor promotes growth arrest and apoptosis in tubular renal cells exposed to Cyclosporine A.	Cyclosporine	131-145	nerve growth factor	Homo sapiens	40-59	
21889978-9	2012	Inhibition of calcineurin-NFAT signalling with cyclosporine-A or 11R-VIVIT abolished the HFES induced NGF down-regulation (NGF: 50 Hz+CsA=1.14, P<0.05).	Cyclosporine	47-61	nerve growth factor	Homo sapiens	102-105