PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25618019-5 2015 The proteins OATP1B1 and OATP1B3 were functionally characterized in stably transfected human embryonic kidney cells using [(3)H] labeled estrone 3-sulfate and [(3)H] labeled cholecystokinin octapeptide (CCK-8) as substrates, respectively. Sincalide 174-201 solute carrier organic anion transporter family member 1B3 Homo sapiens 25-32 23082789-6 2012 In SCHH, the uptake of CCK-8 and pravastatin was found to be associated with the expression of OATP1B3 and OATP1B1, respectively. Sincalide 23-28 solute carrier organic anion transporter family member 1B3 Homo sapiens 95-102 23215050-8 2013 OATP1B3 V1 showed only modest transport activity toward cholecystokin-8 (CCK-8, a prototype OATP1B3 substrate) in contrast to OATP1B3 WT showing a markedly efficient uptake of CCK-8. Sincalide 73-78 solute carrier organic anion transporter family member 1B3 Homo sapiens 0-7 23215050-8 2013 OATP1B3 V1 showed only modest transport activity toward cholecystokin-8 (CCK-8, a prototype OATP1B3 substrate) in contrast to OATP1B3 WT showing a markedly efficient uptake of CCK-8. Sincalide 73-78 solute carrier organic anion transporter family member 1B3 Homo sapiens 92-99 23215050-8 2013 OATP1B3 V1 showed only modest transport activity toward cholecystokin-8 (CCK-8, a prototype OATP1B3 substrate) in contrast to OATP1B3 WT showing a markedly efficient uptake of CCK-8. Sincalide 73-78 solute carrier organic anion transporter family member 1B3 Homo sapiens 92-99 23215050-8 2013 OATP1B3 V1 showed only modest transport activity toward cholecystokin-8 (CCK-8, a prototype OATP1B3 substrate) in contrast to OATP1B3 WT showing a markedly efficient uptake of CCK-8. Sincalide 176-181 solute carrier organic anion transporter family member 1B3 Homo sapiens 0-7 22897388-7 2012 We observed saturable uptake of typical substrates of NTCP and OATPs except for cholecystokinin octapeptide (OATP1B3-selective substrate), and Na(+)-dependent uptake of taurocholate was confirmed. Sincalide 80-107 solute carrier organic anion transporter family member 1B3 Homo sapiens 109-116 26037524-4 2015 The relative activity factors (RAFs) for OATP1B1 and OATP1B3 transporters were calculated from intrinsic clearances obtained by concentration dependent uptake experiments in human hepatocytes and HEK overexpressing cells: RAF1B1 using estrone-3-sulfate and pitavastatine clearances, and RAF1B3 using cholecystokinine octapeptide (CCK-8) clearances. Sincalide 330-335 solute carrier organic anion transporter family member 1B3 Homo sapiens 53-60 34516949-9 2021 Uptake of (3H)-cholecystokinin octapeptide (CCK-8), a specific OATP1B3 substrate, was determined. Sincalide 44-49 solute carrier organic anion transporter family member 1B3 Homo sapiens 63-70 34516949-13 2021 (3H)-CCK-8 accumulation in cells+BC was significantly greater (~5-13 folds, p<0.001) in day 4 SCH with vs. without Ad-OATP1B3-transduction. Sincalide 5-10 solute carrier organic anion transporter family member 1B3 Homo sapiens 118-125