PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29725397-0 2018 Diallyl disulfide effect on the invasion and migration ability of HL-60 cells with a high expression of DJ-1 in the nucleus through the suppression of the Src signaling pathway. diallyl disulfide 0-17 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 155-158 25396727-0 2014 Diallyl disulfide suppresses SRC/Ras/ERK signaling-mediated proliferation and metastasis in human breast cancer by up-regulating miR-34a. diallyl disulfide 0-17 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 29-32 29725397-5 2018 Western blot assays revealed that the expression of DJ-1 in HHDN was inhibited in a time-dependent manner following treatment with DADS for 24, 48 and 72 h. Following DADS treatment, the expression of phosphorylated Src (p-Src) and phosphorylated Fak (p-Fak) were significantly decreased in all groups compared with the untreated groups, however the expression level of Src, Fak and integrin did not change significantly. diallyl disulfide 131-135 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 216-219 29725397-5 2018 Western blot assays revealed that the expression of DJ-1 in HHDN was inhibited in a time-dependent manner following treatment with DADS for 24, 48 and 72 h. Following DADS treatment, the expression of phosphorylated Src (p-Src) and phosphorylated Fak (p-Fak) were significantly decreased in all groups compared with the untreated groups, however the expression level of Src, Fak and integrin did not change significantly. diallyl disulfide 131-135 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 223-226 29725397-5 2018 Western blot assays revealed that the expression of DJ-1 in HHDN was inhibited in a time-dependent manner following treatment with DADS for 24, 48 and 72 h. Following DADS treatment, the expression of phosphorylated Src (p-Src) and phosphorylated Fak (p-Fak) were significantly decreased in all groups compared with the untreated groups, however the expression level of Src, Fak and integrin did not change significantly. diallyl disulfide 131-135 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 223-226 29725397-5 2018 Western blot assays revealed that the expression of DJ-1 in HHDN was inhibited in a time-dependent manner following treatment with DADS for 24, 48 and 72 h. Following DADS treatment, the expression of phosphorylated Src (p-Src) and phosphorylated Fak (p-Fak) were significantly decreased in all groups compared with the untreated groups, however the expression level of Src, Fak and integrin did not change significantly. diallyl disulfide 167-171 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 216-219 29725397-6 2018 Western blot analysis results revealed that following treatment with DADS and Src inhibitor, the expression levels of p-Src and p-Fak significantly decreased in all three groups compared with untreated groups, whereas the expression levels of Src, Fak and integrin did not change significantly. diallyl disulfide 69-73 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 120-123 29725397-6 2018 Western blot analysis results revealed that following treatment with DADS and Src inhibitor, the expression levels of p-Src and p-Fak significantly decreased in all three groups compared with untreated groups, whereas the expression levels of Src, Fak and integrin did not change significantly. diallyl disulfide 69-73 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 120-123 29725397-7 2018 The expression of DJ-1 in HHND was inhibited in time-dependent manner following treatment with DADS and Src inhibitor for 24, 48 and 72 h. Transwell migration and invasion assay results revealed that DADS and Src inhibitors may suppress migration and invasion in leukemic cells, and a combination of the two treatments may result in more efficient suppression. diallyl disulfide 95-99 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 209-212 29725397-8 2018 DADS may downregulate DJ-1-mediated invasion and migration in leukemic cells through suppressing the Src-Fak-Integrin signaling pathway, and the Src inhibitor may enhance the antitumor effect of DADS. diallyl disulfide 0-4 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 101-104 29725397-8 2018 DADS may downregulate DJ-1-mediated invasion and migration in leukemic cells through suppressing the Src-Fak-Integrin signaling pathway, and the Src inhibitor may enhance the antitumor effect of DADS. diallyl disulfide 195-199 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 145-148