PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34750459-5	2021	The interaction of the PBA and diol containing insulin via boronate ester bond and its interchange with glucose was investigated by FT-IR, 1H NMR and XPS.	4-phenylbutyric acid	23-26	insulin	Homo sapiens	47-54	
21195125-8	2011	While other chemical chaperones (glycerol and 4-phenyl butyric acid) also acutely enhanced insulin-induced GLUT4 translocation, these effects were not mediated via changes in GLUT4 endocytosis.	4-phenylbutyric acid	46-67	insulin	Homo sapiens	91-98	
32200516-7	2020	Treatment with the histone deacetylase inhibitor 4-phenylbutyrate (4-PBA) increased the magnitude of insulin response from a 1.2-fold increase in glucose uptake in the untreated state to a 1.4-fold increase after 4-PBA treatment.	4-phenylbutyric acid	49-65	insulin	Homo sapiens	101-108	
32200516-7	2020	Treatment with the histone deacetylase inhibitor 4-phenylbutyrate (4-PBA) increased the magnitude of insulin response from a 1.2-fold increase in glucose uptake in the untreated state to a 1.4-fold increase after 4-PBA treatment.	4-phenylbutyric acid	67-72	insulin	Homo sapiens	101-108	
32200516-7	2020	Treatment with the histone deacetylase inhibitor 4-phenylbutyrate (4-PBA) increased the magnitude of insulin response from a 1.2-fold increase in glucose uptake in the untreated state to a 1.4-fold increase after 4-PBA treatment.	4-phenylbutyric acid	213-218	insulin	Homo sapiens	101-108	
24227685-5	2014	Importantly, 4-phenyl butyric acid, a chemical protein folding and trafficking chaperone, restored normal insulin synthesis and the ability to upregulate insulin secretion.	4-phenylbutyric acid	13-34	insulin	Homo sapiens	106-113	
24227685-5	2014	Importantly, 4-phenyl butyric acid, a chemical protein folding and trafficking chaperone, restored normal insulin synthesis and the ability to upregulate insulin secretion.	4-phenylbutyric acid	13-34	insulin	Homo sapiens	154-161	
21270237-0	2011	Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans.	4-phenylbutyric acid	0-21	insulin	Homo sapiens	125-132	
21270237-3	2011	Here we examined the efficacy of the chemical chaperone, sodium phenylbutyrate (PBA), a drug with known capacity to reduce ER stress in animal models and in vitro, on lipid-induced insulin resistance and beta-cell dysfunction in humans.	4-phenylbutyric acid	57-78	insulin	Homo sapiens	181-188	
20006364-5	2010	Both 4-phenylbutyric acid and glycerol significantly activated protein kinase B, confirming the involvement of endoplasmic reticulum stress in palmitate-mediated insulin resistance.	4-phenylbutyric acid	5-25	insulin	Homo sapiens	162-169	
20165829-6	2010	Interestingly, pretreatment of both rat and human myotubes with the chemical chaperones 4-phenylbutyric acid (PBA) or tauroursodeoxycholic acid (TUDCA), completely prevented the effect of glucosamine on both ER stress induction and insulin-induced glucose uptake.	4-phenylbutyric acid	88-108	insulin	Homo sapiens	232-239	
20165829-6	2010	Interestingly, pretreatment of both rat and human myotubes with the chemical chaperones 4-phenylbutyric acid (PBA) or tauroursodeoxycholic acid (TUDCA), completely prevented the effect of glucosamine on both ER stress induction and insulin-induced glucose uptake.	4-phenylbutyric acid	110-113	insulin	Homo sapiens	232-239