PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28153729-0 2017 4-PBA reverses autophagic dysfunction and improves insulin sensitivity in adipose tissue of obese mice via Akt/mTOR signaling. 4-phenylbutyric acid 0-5 thymoma viral proto-oncogene 1 Mus musculus 107-110 28153729-7 2017 The protective effects of 4-PBA were nullified by suppression of Akt and mTOR in adipocytes, suggesting that 4-PBA inhibits autophagy and restores insulin sensitivity via Akt/mTOR signaling partially. 4-phenylbutyric acid 26-31 thymoma viral proto-oncogene 1 Mus musculus 171-174 28153729-7 2017 The protective effects of 4-PBA were nullified by suppression of Akt and mTOR in adipocytes, suggesting that 4-PBA inhibits autophagy and restores insulin sensitivity via Akt/mTOR signaling partially. 4-phenylbutyric acid 109-114 thymoma viral proto-oncogene 1 Mus musculus 65-68 28153729-7 2017 The protective effects of 4-PBA were nullified by suppression of Akt and mTOR in adipocytes, suggesting that 4-PBA inhibits autophagy and restores insulin sensitivity via Akt/mTOR signaling partially. 4-phenylbutyric acid 109-114 thymoma viral proto-oncogene 1 Mus musculus 171-174 28153729-8 2017 CONCLUSIONS: 4-PBA reverses autophagic dysfunction and improves insulin sensitivity in adipose tissue of obese mice via Akt/mTOR signaling partly, which could be regarded as novel opportunities for treatment of insulin resistance. 4-phenylbutyric acid 13-18 thymoma viral proto-oncogene 1 Mus musculus 120-123