PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15490173-0 2004 Activity of the yeast Tat2p tryptophan permease is sensitive to the anti-tumor agent 4-phenylbutyrate. 4-phenylbutyric acid 85-101 aromatic amino acid transmembrane transporter TAT2 Saccharomyces cerevisiae S288C 22-27 15490173-4 2004 We show here that PB and sorbic acid induce an ubiquitin-dependent turnover of the tryptophan permease Tat2p. 4-phenylbutyric acid 18-20 aromatic amino acid transmembrane transporter TAT2 Saccharomyces cerevisiae S288C 103-108 15490173-8 2004 Our results show that diverse agents affect the activity of the Tat2p permease rather than its stability and suggest the hypothesis that the anti-neoplastic action of PB is due to a decrease in the activity of surface receptors or other membrane proteins needed to maintain the transformed state. 4-phenylbutyric acid 167-169 aromatic amino acid transmembrane transporter TAT2 Saccharomyces cerevisiae S288C 64-69