PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28851073-6 2018 Upregulation of HER3/HER4 and activation of HER3/HER4-ERK pathway was shown to be involved in 4-PBA-induced gastric cancer cell migration. 4-phenylbutyric acid 94-99 mitogen-activated protein kinase 1 Homo sapiens 54-57 29913144-0 2018 Paraquat toxicity is attenuated by 4-phenylbutyrate-induced phosphorylation of ERK2 via PI3K in A549 cells. 4-phenylbutyric acid 35-51 mitogen-activated protein kinase 1 Homo sapiens 79-83 28851073-8 2018 Consistently, the ERK inhibitor PD98059 also partially prevented 4-PBA-induced cell migration. 4-phenylbutyric acid 65-70 mitogen-activated protein kinase 1 Homo sapiens 18-21 28851073-10 2018 These results demonstrate that 4-PBA promotes gastric cancer cells migration through upregulation of HER3/HER4 subsequent to increased levels of acetyl-histone and activation of ERK signaling. 4-phenylbutyric acid 31-36 mitogen-activated protein kinase 1 Homo sapiens 178-181 15389886-6 2004 We observed activation of JNK and ERK by PB in the lung cancer cells. 4-phenylbutyric acid 41-43 mitogen-activated protein kinase 1 Homo sapiens 34-37 31814524-7 2020 Knockdown of IL-8 partially prevented 4-PBA-induced-EMT by blocking the activation of the downstream Gab2-ERK pathway. 4-phenylbutyric acid 38-43 mitogen-activated protein kinase 1 Homo sapiens 106-109 31814524-9 2020 Therefore, the results of this study demonstrated that 4-PBA-mediated inhibition of HDAC activity could induce EMT in gastric cancer cells via acetyl-histone-mediated IL-8 upregulation, and the downstream Gab2/ERK activation. 4-phenylbutyric acid 55-60 mitogen-activated protein kinase 1 Homo sapiens 210-213