PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30041247-13	2018	Additionally, the inhibition of ERS with 4-PBA suppressed the expression of HMGB-1-induced CHOP.	4-phenylbutyric acid	41-46	DNA-damage inducible transcript 3	Mus musculus	91-95	
29196971-7	2018	Pretreatment with 4-phenylbutyric acid (a chemical chaperone) also inhibited TNF-alpha-induced cleavage of caspase 3 and PARP and up-regulation of ATF4 and CHOP expression.	4-phenylbutyric acid	18-38	DNA-damage inducible transcript 3	Mus musculus	156-160	
28807099-12	2017	Furthermore, 4-PBA treatment inhibited silica-induced endoplasmic reticulum expansion and the expression of BiP and CHOP.	4-phenylbutyric acid	13-18	DNA-damage inducible transcript 3	Mus musculus	116-120	
28798155-9	2017	Moreover, after 4-PBA or T0 administration, the number of CD68+p-eIIF2alpha+ and CD68+CHOP+ double-positive cells in neointimal was also apparently decreased.	4-phenylbutyric acid	16-21	DNA-damage inducible transcript 3	Mus musculus	86-90	
26176291-8	2015	In addition, blocking ERS using 4-phenylbutyric acid (4-PBA) not only downregulated the expression of PERK, ATF4 and CHOP, but also significantly decreased apoptosis induced by HRC silence, whereas ERS inducer thapsigargin (TG) exerted the opposite effects.	4-phenylbutyric acid	32-52	DNA-damage inducible transcript 3	Mus musculus	117-121	
26999661-6	2016	These beneficial effects of UDCA or 4-PBA on DN were associated with the inhibition of ER stress, as evidenced by the decreased expression of BiP, phospho-IRE1alpha, phospho-eIF2alpha, CHOP, ATF-6 and spliced X-box binding protein-1 in vitro and in vivo.	4-phenylbutyric acid	36-41	DNA-damage inducible transcript 3	Mus musculus	185-189	
26176291-8	2015	In addition, blocking ERS using 4-phenylbutyric acid (4-PBA) not only downregulated the expression of PERK, ATF4 and CHOP, but also significantly decreased apoptosis induced by HRC silence, whereas ERS inducer thapsigargin (TG) exerted the opposite effects.	4-phenylbutyric acid	54-59	DNA-damage inducible transcript 3	Mus musculus	117-121	
33548116-10	2021	Induction of CHOP, autophagosomal protein LC3-II and cell death by this mutant were abrogated by Tbk1 knockdown, and also by 4-phenylbutyric acid, that inhibits ER stress.	4-phenylbutyric acid	125-145	DNA-damage inducible transcript 3	Mus musculus	13-17	
34356380-6	2021	Induction of retinal ER stress soon after light exposure, represented by upregulation of the immunoglobulin heavy chain binding protein (BiP) and C/EBP-Homologous Protein (CHOP), were suppressed by 4-PBA.	4-phenylbutyric acid	198-203	DNA-damage inducible transcript 3	Mus musculus	146-170	
34356380-6	2021	Induction of retinal ER stress soon after light exposure, represented by upregulation of the immunoglobulin heavy chain binding protein (BiP) and C/EBP-Homologous Protein (CHOP), were suppressed by 4-PBA.	4-phenylbutyric acid	198-203	DNA-damage inducible transcript 3	Mus musculus	172-176	
32123584-7	2020	Instead, delivery of the chemical chaperone 4-phenyl-butyrate (PBA) to Hepa1-6 cells treated with elevated palmitate, while increasing abundance of Grp78/BiP protein and restoring membrane glycosylation, also increased ERQC, expression and nuclear translocation of CHOP, non-mitochondrial oxygen consumption, and generation of ROS.	4-phenylbutyric acid	44-61	DNA-damage inducible transcript 3	Mus musculus	265-269	
31766455-7	2019	Moreover, 4-phenylbutyrate (4-PBA), an ER stress inhibitor, significantly decreased GRP78, CHOP, and ERO1alpha expression, and inhibited cell apoptosis in RAW 264.7 macrophage cells.	4-phenylbutyric acid	10-26	DNA-damage inducible transcript 3	Mus musculus	91-95	
31766455-7	2019	Moreover, 4-phenylbutyrate (4-PBA), an ER stress inhibitor, significantly decreased GRP78, CHOP, and ERO1alpha expression, and inhibited cell apoptosis in RAW 264.7 macrophage cells.	4-phenylbutyric acid	28-33	DNA-damage inducible transcript 3	Mus musculus	91-95	
31406023-4	2019	Moreover, inhibition of ER stress by 4-phenylbutyrate (4-PBA) attenuated thapsigargin-(TG, ER stress agonist) or LPS-induced reduction of Cyp19a1 and E2, pro-inflammatory cytokines expression (IL-1beta, IL-6, IL-8, and TNF-alpha), and the expression of CHOP and GRP78.	4-phenylbutyric acid	37-53	DNA-damage inducible transcript 3	Mus musculus	253-257	
31406023-4	2019	Moreover, inhibition of ER stress by 4-phenylbutyrate (4-PBA) attenuated thapsigargin-(TG, ER stress agonist) or LPS-induced reduction of Cyp19a1 and E2, pro-inflammatory cytokines expression (IL-1beta, IL-6, IL-8, and TNF-alpha), and the expression of CHOP and GRP78.	4-phenylbutyric acid	55-60	DNA-damage inducible transcript 3	Mus musculus	253-257