PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32805694-0 2020 Inhibition of GPR17 with pranlukast protects against TNF-alpha-induced loss of type II collagen in ATDC5 cells. pranlukast 25-35 tumor necrosis factor Mus musculus 53-62 32805694-7 2020 We also found that antagonism of GPR17 with pranlukast significantly inhibited oxidative stress by downregulating the intracellular level of reactive oxygen species (ROS) and increasing the activity of super oxide dismutase (SOD) against TNF-alpha. pranlukast 44-54 tumor necrosis factor Mus musculus 238-247 32805694-8 2020 Interestingly, treatment with pranlukast prevented TNF-alpha-induced reduction of type II collagen. pranlukast 30-40 tumor necrosis factor Mus musculus 51-60 32805694-12 2020 Furthermore, pranlukast rescued TNF-alpha-induced reduced SOX-9 expression. pranlukast 13-23 tumor necrosis factor Mus musculus 32-41