PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24229499-8 2014 Furthermore, pranlukast reversed Abeta1-42-induced CysLT1R upregulation, and markedly suppressed the Abeta1-42-triggered NF-kappaB pathway, caspase-3 activation and Bcl-2 downregulation in the hippocampus and prefrontal cortex in mice. pranlukast 13-23 caspase 3 Mus musculus 140-149 24269024-5 2014 The CysLT1R antagonist pranlukast not only reversed Abeta1-42-induced upregulation of CysLT1R, but also suppressed Abeta1-42-triggered neurotoxicity evidenced by enhanced nuclear factor-kappa B p65, activated caspase-3, decreased B-cell lymphoma-2 and cell viability and impaired memory. pranlukast 23-33 caspase 3 Mus musculus 209-218