PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14653951-7 2003 ONO-1078 (0.1, 0.3 mg/kg) significantly inhibited the enhanced expression of NMDA receptor subunit protein NR2A in the cortex and VCAM-1 in the hippocampus of ischemic rats. pranlukast 0-8 glutamate ionotropic receptor NMDA type subunit 2A Rattus norvegicus 107-111 14653951-8 2003 CONCLUSION: ONO-1078 possesses a neuroprotective effect on global cerebral ischemia in rats, and its mechanism may be partly related to the inhibition of the upregulation of NR2A and VCAM-1 in different regions of the brain. pranlukast 12-20 glutamate ionotropic receptor NMDA type subunit 2A Rattus norvegicus 174-178