PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15127571-0 2004 [Protective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia induced by endothelin-1 in rats]. pranlukast 22-30 endothelin 1 Rattus norvegicus 105-117 15127571-1 2004 AIM: To determine the protective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia induced by endothelin-1 in rats. pranlukast 43-51 endothelin 1 Rattus norvegicus 126-138 15127571-7 2004 In rats pretreated with ONO-1078, endothelin-1-induced brain edema and brain infarction size were decreased. pranlukast 24-32 endothelin 1 Rattus norvegicus 34-46 15127571-10 2004 CONCLUSION: ONO-1078 possesses neuroprotective effect against cerebral ischemic injury induced by endothelin-1, therefore, leukotrienes may play a role in the injury of cerebral ischemia. pranlukast 12-20 endothelin 1 Rattus norvegicus 98-110