PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26101157-4 2015 We found that using doxycycline to control Pgp expression has a significant advantage over tetracycline, in that doxycycline caused less endogenous gene expression modification/perturbation, and was more potent than tetracycline in suppressing Pgp expression. Tetracycline 216-228 ATP binding cassette subfamily B member 1 Homo sapiens 43-46 26101157-4 2015 We found that using doxycycline to control Pgp expression has a significant advantage over tetracycline, in that doxycycline caused less endogenous gene expression modification/perturbation, and was more potent than tetracycline in suppressing Pgp expression. Tetracycline 216-228 ATP binding cassette subfamily B member 1 Homo sapiens 244-247 12810633-4 2003 Therefore, we created two cell lines in which a transfected human MDR1 cDNA is repressed by tetracycline and induced in the absence of tetracycline. Tetracycline 92-104 ATP binding cassette subfamily B member 1 Homo sapiens 66-70 23774624-6 2013 To this end we focused our study on HeLa cells carrying a tetracycline-repressible plasmid system which shuts down Pgp expression in the presence of tetracycline. Tetracycline 58-70 ATP binding cassette subfamily B member 1 Homo sapiens 115-118 23774624-6 2013 To this end we focused our study on HeLa cells carrying a tetracycline-repressible plasmid system which shuts down Pgp expression in the presence of tetracycline. Tetracycline 149-161 ATP binding cassette subfamily B member 1 Homo sapiens 115-118 12810633-4 2003 Therefore, we created two cell lines in which a transfected human MDR1 cDNA is repressed by tetracycline and induced in the absence of tetracycline. Tetracycline 135-147 ATP binding cassette subfamily B member 1 Homo sapiens 66-70 11147995-0 2000 Functional and histochemical analysis of MDR3 P-glycoprotein in a tetracycline-controlled gene expression system. Tetracycline 66-78 ATP binding cassette subfamily B member 1 Homo sapiens 46-60 8093660-0 1993 Resistance to tetracycline, a hydrophilic antibiotic, is mediated by P-glycoprotein in human multidrug-resistant cells. Tetracycline 14-26 ATP binding cassette subfamily B member 1 Homo sapiens 69-83 8093660-5 1993 Although drugs associated with the multidrug-resistance phenotype are typically hydrophobic compounds, these data suggest that resistance to tetracycline, despite its hydrophilic nature, is mediated by P-glycoprotein in these cell lines. Tetracycline 141-153 ATP binding cassette subfamily B member 1 Homo sapiens 202-216