PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21135157-3	2010	In this study, we employed a tetracycline-inducible CREB repressor mouse strain, in which approximately 60% of the SCN neurons express the transgene, to test CREB functionality in the clock and its effects on overt rhythmicity.	Tetracycline	29-41	cAMP responsive element binding protein 1	Mus musculus	52-56	
19435810-1	2009	We used a double transgenic tetracycline system to conditionally express A-CREB, a dominant negative protein that prevents the DNA binding and function of cAMP-responsive element binding protein (CREB) family members, in mouse basal epidermis using the keratin 5 promoter.	Tetracycline	28-40	cAMP responsive element binding protein 1	Mus musculus	75-79	
15176089-5	2004	We generated two independent strains of nestin-tTA transgenic animals and crossed founder mice from both lines to mice containing a tetracycline-regulated transgene (mCREB) whose expression served as a marker for the activity of the nestin-tTA transgene.	Tetracycline	132-144	cAMP responsive element binding protein 1	Mus musculus	166-171	
12021407-1	2002	To investigate the role of cAMP response element-binding protein (CREB) in the adaptive responses to psychotropic drugs, we have developed inducible, brain region-specific CREB transgenic mice using the tetracycline-regulated gene expression system.	Tetracycline	203-215	cAMP responsive element binding protein 1	Mus musculus	66-70	
12021407-1	2002	To investigate the role of cAMP response element-binding protein (CREB) in the adaptive responses to psychotropic drugs, we have developed inducible, brain region-specific CREB transgenic mice using the tetracycline-regulated gene expression system.	Tetracycline	203-215	cAMP responsive element binding protein 1	Mus musculus	172-176	
12021407-3	2002	Different patterns of CREB overexpression were found in striatum, nucleus accumbens, and cingulate cortex in different lines of bitransgenic mice, and CREB expression was blocked by addition of doxycycline, an analog of tetracycline.	Tetracycline	220-232	cAMP responsive element binding protein 1	Mus musculus	22-26	
12021407-3	2002	Different patterns of CREB overexpression were found in striatum, nucleus accumbens, and cingulate cortex in different lines of bitransgenic mice, and CREB expression was blocked by addition of doxycycline, an analog of tetracycline.	Tetracycline	220-232	cAMP responsive element binding protein 1	Mus musculus	151-155