PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11767279-0	2001	An adenoviral system for tetracycline-regulated TGF-beta expression mediates a reversible cell cycle arrest.	Tetracycline	25-37	transforming growth factor beta 1	Homo sapiens	48-56	
11767279-5	2001	We have adapted the tetracycline-regulated expression system to allow regulated transforming growth factor (TGF)-beta1 expression using recombinant adenovirus.	Tetracycline	20-32	transforming growth factor beta 1	Homo sapiens	80-118	
9454891-5	1998	Furthermore, inhibition of kdT beta RII expression by tetracycline treatment led to TGF-beta 1-mediated cell growth arrest in the G1 phase of cell cycle and to the accumulation of the hypophosphorylated form of retinoblastoma (Rb) protein.	Tetracycline	54-66	transforming growth factor beta 1	Homo sapiens	84-94	
9139748-5	1997	Treatment with tetracycline suppressed RIII expression and abolished TGFbeta1 binding to RI and RII.	Tetracycline	15-27	transforming growth factor beta 1	Homo sapiens	69-77	
9079651-5	1997	Although the TGF-beta1 response was blocked by removal of tetracycline in MCF-7/DeltaRII cells, tamoxifen-mediated suppression of Rb phosphorylation, recruitment in G1, and inhibition of cell proliferation were identical in the presence and absence of tetracycline.	Tetracycline	58-70	transforming growth factor beta 1	Homo sapiens	13-22	
8668164-6	1996	Indeed, inducible expression, under control of a tetracycline-regulated promoter, of D404G-TbetaRII in TGF-beta- sensitive Mac-1 cells as well as in Hep3B hepatoma cells results in resistance to TGF-beta and disappearance of cell surface TbetaRI and TbetaRII.	Tetracycline	49-61	transforming growth factor beta 1	Homo sapiens	103-111	
8668164-6	1996	Indeed, inducible expression, under control of a tetracycline-regulated promoter, of D404G-TbetaRII in TGF-beta- sensitive Mac-1 cells as well as in Hep3B hepatoma cells results in resistance to TGF-beta and disappearance of cell surface TbetaRI and TbetaRII.	Tetracycline	49-61	transforming growth factor beta 1	Homo sapiens	195-203	
15059906-9	2004	Tetracycline treatment of RII transfectants led to the suppression of p21/waf1/cip1and p27/kip expression, thus, directly demonstrating induction of CDK inhibitors by autocrine TGF-beta leading to growth control of ER(+) breast cancer cells.	Tetracycline	0-12	transforming growth factor beta 1	Homo sapiens	177-185	
11846446-4	2002	To study the mechanisms of these effects, a tetracycline-inducible expression system was used to overexpress type II TGF-beta receptors in NIH 3T3 fibroblasts.	Tetracycline	44-56	transforming growth factor beta 1	Homo sapiens	117-125	
11767279-6	2001	We demonstrate that infection with a recombinant TGF-beta-encoding virus system in primary human oral keratinocytes and in a lung epithelial cell line is sufficient to allow a cell cycle arrest that is reversible upon tetracycline addition.	Tetracycline	218-230	transforming growth factor beta 1	Homo sapiens	49-57