PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9744295-5 1998 Because the constitutive overexpression of SSeCKS is toxic [Lin et al., 1995], we developed cell lines with tetracycline (tet)-regulated SSeCKS expression. Tetracycline 108-120 A-kinase anchoring protein 12 Homo sapiens 43-49 9744295-5 1998 Because the constitutive overexpression of SSeCKS is toxic [Lin et al., 1995], we developed cell lines with tetracycline (tet)-regulated SSeCKS expression. Tetracycline 108-120 A-kinase anchoring protein 12 Homo sapiens 137-143 9744295-5 1998 Because the constitutive overexpression of SSeCKS is toxic [Lin et al., 1995], we developed cell lines with tetracycline (tet)-regulated SSeCKS expression. Tetracycline 108-111 A-kinase anchoring protein 12 Homo sapiens 43-49 9744295-5 1998 Because the constitutive overexpression of SSeCKS is toxic [Lin et al., 1995], we developed cell lines with tetracycline (tet)-regulated SSeCKS expression. Tetracycline 108-111 A-kinase anchoring protein 12 Homo sapiens 137-143 9744295-6 1998 The induction of SSeCKS (removal of tet) caused significant cell flattening and the elaboration of an SSeCKS-associated cortical cytoskeletal matrix resistant to Triton X-100 extraction. Tetracycline 36-39 A-kinase anchoring protein 12 Homo sapiens 17-23 9744295-6 1998 The induction of SSeCKS (removal of tet) caused significant cell flattening and the elaboration of an SSeCKS-associated cortical cytoskeletal matrix resistant to Triton X-100 extraction. Tetracycline 36-39 A-kinase anchoring protein 12 Homo sapiens 102-108 16740695-1 2006 SSeCKS, a Src-suppressed protein kinase C substrate with metastasis suppressor activity, is the rodent orthologue of human gravin/AKAP12, a scaffolding protein for protein kinase A and protein kinase C. We show here that the tetracycline-regulated reexpression of SSeCKS in MatLyLu (MLL) prostate cancer cells suppressed formation of macroscopic lung metastases in both spontaneous and experimental models of in vivo metastasis while having minimal inhibitory effects on the growth of primary-site s.c. tumors. Tetracycline 225-237 A-kinase anchoring protein 12 Homo sapiens 0-6 16740695-1 2006 SSeCKS, a Src-suppressed protein kinase C substrate with metastasis suppressor activity, is the rodent orthologue of human gravin/AKAP12, a scaffolding protein for protein kinase A and protein kinase C. We show here that the tetracycline-regulated reexpression of SSeCKS in MatLyLu (MLL) prostate cancer cells suppressed formation of macroscopic lung metastases in both spontaneous and experimental models of in vivo metastasis while having minimal inhibitory effects on the growth of primary-site s.c. tumors. Tetracycline 225-237 A-kinase anchoring protein 12 Homo sapiens 130-136 16740695-1 2006 SSeCKS, a Src-suppressed protein kinase C substrate with metastasis suppressor activity, is the rodent orthologue of human gravin/AKAP12, a scaffolding protein for protein kinase A and protein kinase C. We show here that the tetracycline-regulated reexpression of SSeCKS in MatLyLu (MLL) prostate cancer cells suppressed formation of macroscopic lung metastases in both spontaneous and experimental models of in vivo metastasis while having minimal inhibitory effects on the growth of primary-site s.c. tumors. Tetracycline 225-237 A-kinase anchoring protein 12 Homo sapiens 264-270