PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29386392-3 2018 Here we develop human tyrosine hydroxylase (TH) promoter-controlled tetracycline-sensitive LRRK2 G2019S (GS) and LRRK2 G2019S kinase-dead (GS/DA) transgenic mice and show that LRRK2 GS expression leads to an age- and kinase-dependent cell-autonomous neurodegeneration of DA and norepinephrine (NE) neurons. Tetracycline 68-80 leucine rich repeat kinase 2 Homo sapiens 91-96