PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16202037-3 2005 The tetracycline-controlled double-transgenic TA(LAP-2)/p(tet)TGF-beta1 mouse provides a model for reversible liver fibrosis. Tetracycline 4-16 transforming growth factor, beta 1 Mus musculus 62-71 20616344-1 2010 We recently showed in a tetracycline-controlled transgenic mouse model that overexpression of transforming growth factor (TGF)-beta1 in renal tubules induces widespread peritubular fibrosis and focal degeneration of nephrons. Tetracycline 24-36 transforming growth factor, beta 1 Mus musculus 94-132 16386398-2 2006 Recently, we have established a transgenic mouse model with inducible neuron-specific expression of TGF-beta1 based on the tetracycline-regulated gene expression system. Tetracycline 123-135 transforming growth factor, beta 1 Mus musculus 100-109 16288910-5 2006 Therefore, to overexpress TGF-beta1 in the artery wall of adult mice, we generated mice that were transgenic for a conditional, tetracycline operator (tetO)-driven TGF-beta1 allele. Tetracycline 128-140 transforming growth factor, beta 1 Mus musculus 164-173 16288910-6 2006 These mice were viable, and when crossed with mice expressing a tetracycline-regulated transactivator (tTA) in the heart, expressed the TGF-beta1 transgene in a cardiac-restricted and doxycycline-dependent manner. Tetracycline 64-76 transforming growth factor, beta 1 Mus musculus 136-145 15246211-0 2004 Reduction and expansion of the glutamine synthetase expressing zone in livers from tetracycline controlled TGF-beta1 transgenic mice and multiple starved mice. Tetracycline 83-95 transforming growth factor, beta 1 Mus musculus 107-116 16029195-4 2005 To overcome these limitations, we established a transgenic mouse model with inducible neuron-specific expression of TGF-beta1 based on the tetracycline-regulated gene expression system. Tetracycline 139-151 transforming growth factor, beta 1 Mus musculus 116-125 15246211-1 2004 BACKGROUND/AIMS: To learn more about tissue remodelling in fibrotic livers of tetracycline-controlled TGF-beta1 transgenic mice (TGF-beta1-on-mice) and during regeneration after removal of the fibrotic stimulus (off-mice), we investigated the expression of glutamine synthetase (GS), an exclusive pericentrally expressed enzyme. Tetracycline 78-90 transforming growth factor, beta 1 Mus musculus 102-111 12714527-6 2003 Examination of KC mRNA expressed under control of a tetracycline-responsive promoter demonstrated that TGFbeta prevented stabilization of KC mRNA, in response to LPS but did not alter KC mRNA half-life directly. Tetracycline 52-64 transforming growth factor, beta 1 Mus musculus 103-110 12717387-0 2003 Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis. Tetracycline 12-24 transforming growth factor, beta 1 Mus musculus 49-58 12717387-1 2003 Based on the tetracycline-regulated gene expression system, a double-transgenic mouse model for liver fibrosis was established in which the expression of transforming growth factor beta1 (TGF-beta1) can be regulated deliberately by addition or removal of doxycycline hydrochloride to the drinking water. Tetracycline 13-25 transforming growth factor, beta 1 Mus musculus 154-186 12717387-1 2003 Based on the tetracycline-regulated gene expression system, a double-transgenic mouse model for liver fibrosis was established in which the expression of transforming growth factor beta1 (TGF-beta1) can be regulated deliberately by addition or removal of doxycycline hydrochloride to the drinking water. Tetracycline 13-25 transforming growth factor, beta 1 Mus musculus 188-197