PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27307593-5 2016 EXPERIMENTAL DESIGN AND RESULTS: Buparlisib inhibited AKT activity, decreased proliferation, and induced apoptosis in metastatic melanoma cell lines and short-term brain melanoma cells, irrespective of their BRAF and NRAS mutation status. NVP-BKM120 33-43 NRAS proto-oncogene, GTPase Homo sapiens 217-221 27307593-7 2016 The growth of tumors induced by injecting human BRAF- and NRAS-mutant metastatic melanoma cells into the brain of mice was significantly inhibited by buparlisib. NVP-BKM120 150-160 NRAS proto-oncogene, GTPase Homo sapiens 58-62