PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26673665-7	2015	BKM120 activity induced the blockage of PI3K/AKT signaling and NF-kappaB expression, which in turn led to activate caspase-3/7 and caspase-9 and changed the expression of several apoptosis-related gene expression.	NVP-BKM120	0-6	caspase 3	Homo sapiens	115-126	
30401630-2	2019	Our results outlined that abrogation of PI3K using pan-PI3K inhibitor BKM120 decreased survival of MM cells through induction of a caspase-3-dependent apoptosis coupled with SIRT1-mediated G2/M arrest in both KMM-1 and RPMI 8226 cell lines; however, the cell responses to the inhibitor was quite different, introducing wild-type PTEN-expressing RPMI 8226 as less sensitive cells.	NVP-BKM120	70-76	caspase 3	Homo sapiens	131-140	
30536897-6	2019	All OS cell lines used in this study responded to BKM120 treatment with an arrest of cell proliferation, an increase in cell mortality, and an increase in caspase-3 activity.	NVP-BKM120	50-56	caspase 3	Homo sapiens	155-164