PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30703376-4 2019 In the present work, the effects of buparlisib were tested on six human recombinant carbonyl-reducing enzymes: AKR1A1, AKR1B1, AKR1B10, AKR1C3, and AKR7A2 from the aldo-keto reductase superfamily and CBR1 from the short-chain dehydrogenase/reductase superfamily, all of which participate in the metabolism of daunorubicin. NVP-BKM120 36-46 aldo-keto reductase family 1 member B10 Homo sapiens 127-134