PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25736722-1	2015	A new series of icariin derivatives were synthesized and evaluated for their in vitro acetylcholinesterase (AChE) inhibitory activity.	icariin	16-23	acetylcholinesterase (Cartwright blood group)	Homo sapiens	86-106	
25736722-1	2015	A new series of icariin derivatives were synthesized and evaluated for their in vitro acetylcholinesterase (AChE) inhibitory activity.	icariin	16-23	acetylcholinesterase (Cartwright blood group)	Homo sapiens	108-112	
23227542-2	2012	The inhibitory effect of icariin on the activity of AChE was investigated by inhibition kinetics.	icariin	25-32	acetylcholinesterase (Cartwright blood group)	Homo sapiens	52-56	
23227542-4	2012	The results showed that icariin could potently inhibit the activity of AChE, the IC50 value was determined to be 3.50 x 10(-8) mol x L(-1), and the determined IC50 value to tacrine was 0.75 x 10(-8) mol x L(-1).	icariin	24-31	acetylcholinesterase (Cartwright blood group)	Homo sapiens	71-75	
23227542-5	2012	Kinetic analyses showed that icariin is a reversible and mixed type AChE inhibitor.	icariin	29-36	acetylcholinesterase (Cartwright blood group)	Homo sapiens	68-72	
23227542-7	2012	Icariin binds selectively to the AChE peripheral anionic site via hydrogen bonds and Van der Waals forces.	icariin	0-7	acetylcholinesterase (Cartwright blood group)	Homo sapiens	33-37