PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18623213-2 2009 Previous work has shown that amphiphilic diblock copolymers composed of methoxypolyethylene glycol-block-polycaprolactone (MePEG-b-PCL) diblock copolymers enhanced the cellular accumulation of Pgp substrates by modulating the function of this drug efflux transporter. diblock copolymers 41-59 ATP binding cassette subfamily B member 1 Homo sapiens 193-196 18623213-2 2009 Previous work has shown that amphiphilic diblock copolymers composed of methoxypolyethylene glycol-block-polycaprolactone (MePEG-b-PCL) diblock copolymers enhanced the cellular accumulation of Pgp substrates by modulating the function of this drug efflux transporter. diblock copolymers 136-154 ATP binding cassette subfamily B member 1 Homo sapiens 193-196 18623213-3 2009 The objective of this work was to determine whether MePEG-b-PCL diblock copolymers modulated Pgp function in multidrug resistant (MDR) cancer cells. diblock copolymers 64-82 ATP binding cassette subfamily B member 1 Homo sapiens 93-96 18380467-0 2008 P-glycoprotein efflux inhibition by amphiphilic diblock copolymers: relationship between copolymer concentration and substrate hydrophobicity. diblock copolymers 48-66 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 18380467-3 2008 Therefore, the objectives of these studies were to assess if association of P-gp substrates differing in hydrophobicity will impact the effective concentration range for P-gp inhibition by amphiphilic diblock copolymers based on methoxypolyethylene glycol-block-polycaprolatone (MePEG-b-PCL). diblock copolymers 201-219 ATP binding cassette subfamily B member 1 Homo sapiens 76-80 18380467-3 2008 Therefore, the objectives of these studies were to assess if association of P-gp substrates differing in hydrophobicity will impact the effective concentration range for P-gp inhibition by amphiphilic diblock copolymers based on methoxypolyethylene glycol-block-polycaprolatone (MePEG-b-PCL). diblock copolymers 201-219 ATP binding cassette subfamily B member 1 Homo sapiens 170-174 12445560-1 2002 A series of diblock copolymers based on methoxypolyethylene glycol-block-poly(caprolactone) (MePEG-b-PCL) was synthesized and evaluated for enhancing the cellular accumulation of a P-glycoprotein (P-gp) substrate, rhodamine-123 (R-123), into caco-2 cells. diblock copolymers 12-30 ATP binding cassette subfamily B member 1 Homo sapiens 181-195 12445560-1 2002 A series of diblock copolymers based on methoxypolyethylene glycol-block-poly(caprolactone) (MePEG-b-PCL) was synthesized and evaluated for enhancing the cellular accumulation of a P-glycoprotein (P-gp) substrate, rhodamine-123 (R-123), into caco-2 cells. diblock copolymers 12-30 ATP binding cassette subfamily B member 1 Homo sapiens 197-201