PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33643049-0 2021 Combination of Ginsenosides Rb2 and Rg3 Promotes Angiogenic Phenotype of Human Endothelial Cells via PI3K/Akt and MAPK/ERK Pathways. ginsenoside Rg3 36-39 mitogen-activated protein kinase 1 Homo sapiens 114-118 33643049-0 2021 Combination of Ginsenosides Rb2 and Rg3 Promotes Angiogenic Phenotype of Human Endothelial Cells via PI3K/Akt and MAPK/ERK Pathways. ginsenoside Rg3 36-39 mitogen-activated protein kinase 1 Homo sapiens 119-122 33643049-11 2021 The present study provides the hypothesis that SBP, via ginsenosides Rb2 and Rg3, involves the CXCR1/2 CXCL8 (IL8)-mediated PI3K/Akt and MAPK/ERK signaling pathways in achieving its proangiogenic effects. ginsenoside Rg3 77-80 mitogen-activated protein kinase 1 Homo sapiens 137-141 33643049-11 2021 The present study provides the hypothesis that SBP, via ginsenosides Rb2 and Rg3, involves the CXCR1/2 CXCL8 (IL8)-mediated PI3K/Akt and MAPK/ERK signaling pathways in achieving its proangiogenic effects. ginsenoside Rg3 77-80 mitogen-activated protein kinase 1 Homo sapiens 142-145 35219164-8 2022 We therefore proceeded to identify which MAPK signaling pathway was involved in G-Rg3-mediated cytolytic activity. ginsenoside Rg3 80-85 mitogen-activated protein kinase 1 Homo sapiens 41-45 35219164-9 2022 Treatment with G-Rg3 increased the phosphorylation levels of extracellular signal-regulated kinase (ERK), whereas ERK inhibition eliminated G-Rg3-induced NK cell cytotoxicity, suggesting the involvement of the ERK pathway. ginsenoside Rg3 15-20 mitogen-activated protein kinase 1 Homo sapiens 61-98 35219164-9 2022 Treatment with G-Rg3 increased the phosphorylation levels of extracellular signal-regulated kinase (ERK), whereas ERK inhibition eliminated G-Rg3-induced NK cell cytotoxicity, suggesting the involvement of the ERK pathway. ginsenoside Rg3 15-20 mitogen-activated protein kinase 1 Homo sapiens 100-103 35219164-11 2022 The G-Rg3 isomer, 20(R)-Rg3, effectively activated NK cells via the extracellular signal-regulated kinase (ERK) signaling pathway, whereas 20(S)-Rg3 had no effect on NK cell activity. ginsenoside Rg3 4-9 mitogen-activated protein kinase 1 Homo sapiens 107-110