PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31434432-11 2019 Conclusions: CIH induces significant atrial remodeling in this rat model, which can be attenuated by tolvaptan possibly through modulating miRNA-21/Spry1/ERK/MMP-9 and miRNA-21/PTEN/PI3K/AKT signaling pathways. Tolvaptan 101-110 matrix metallopeptidase 9 Rattus norvegicus 158-163 30703371-6 2019 What"s more, tolvaptan increased the expression of ZO-1 and occludin (p < 0.05, vs vehicle), which might be attributed to the down-regulated effects of tolvaptan on MMP-9. Tolvaptan 13-22 matrix metallopeptidase 9 Rattus norvegicus 168-173 30703371-6 2019 What"s more, tolvaptan increased the expression of ZO-1 and occludin (p < 0.05, vs vehicle), which might be attributed to the down-regulated effects of tolvaptan on MMP-9. Tolvaptan 155-164 matrix metallopeptidase 9 Rattus norvegicus 168-173 30203914-10 2018 These changes may be explained due to alterations in miR-21/Spry1/ERK/MMP-9, miR-21/PTEN/PI3K/AKT, and NF-kappaB pathways by tolvaptan. Tolvaptan 125-134 matrix metallopeptidase 9 Rattus norvegicus 70-75