PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29128962-11	2018	Responders of tolvaptan have lower BUN and renin activity at baseline, and shorten hospitalization period.	Tolvaptan	14-23	renin	Homo sapiens	43-48	
17703139-9	2007	At 24 hours postdose, plasma renin activity was increased after furosemide or HCTZ administered alone or with tolvaptan, but it was unchanged after tolvaptan alone.	Tolvaptan	110-119	renin	Homo sapiens	29-34	
27818782-11	2016	CONCLUSIONS: As compared with furosemide, tolvaptan in patients with acute heart failure is associated with comparable decongestion, better preservation of renal function and less activation of renin-angiotensin system.	Tolvaptan	42-51	renin	Homo sapiens	194-199	
27515480-8	2016	CONCLUSIONS: Plasma TLV concentrations correlated with the urine volume in late phase of treatment but not in early phase, which suggests that the effect of TLV may possibly be inhibited by renin-angiotensin-aldosterone system activity.	Tolvaptan	20-23	renin	Homo sapiens	190-195	
27515480-8	2016	CONCLUSIONS: Plasma TLV concentrations correlated with the urine volume in late phase of treatment but not in early phase, which suggests that the effect of TLV may possibly be inhibited by renin-angiotensin-aldosterone system activity.	Tolvaptan	157-160	renin	Homo sapiens	190-195