PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31375130-6 2019 For example, tofacitinib and upadacitinib were the most potent inhibitors of the JAK1/3-dependent cytokines tested (interleukin [IL]-2, IL-4, IL-15, and IL-21) with lower IC50 values and increased time above IC50 translating to a greater overall inhibition of STAT signaling during the dosing interval. upadacitinib 29-41 interleukin 15 Homo sapiens 142-147