PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28169456-6 2017 DADS in 1, 5, 10, and 25 muM concentrations had no cytotoxic effect after 24 h. Pretreatment with DADS remarkably increased Nrf2 nuclear translocation as well as the genes expression of detoxifying phase II/antioxidant enzymes and reduced IL-1beta-induced elevation of ROS, lipid peroxidation, Bax/Bcl-2 ratio, caspase-3 activation, and JNK and P38 phosphorylation. amsonic acid 98-102 BCL2 associated X, apoptosis regulator Homo sapiens 294-297 22638860-6 2012 We demonstrated that co-infusion of 6-OHDA with adenovirus expressing siRNA of iNOS blocked the activation of microglia, iNOS transcription, and p53-Bax-CC3 apoptotic cascade as well as significantly blocking 6-OHDA-induced decreases in DA, DOPAC, HVA, and TH levels and effectively decreased rotation number. amsonic acid 40-42 BCL2 associated X, apoptosis regulator Homo sapiens 149-152